Kim Won-Young, Lee Jinmi, Lee Ju-Ry, Jung Youn Kyung, Kim Hwa Jung, Huh Jin Won, Lim Chae-Man, Koh Younsuck, Hong Sang-Bum
Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-Gil, Songpa-gu, Seoul 05505, Republic of Korea.
Medical Emergency Team, Asan Medical Center, 88 Olympic-ro 43-Gil, Songpa-gu, Seoul 05505, Republic of Korea.
J Crit Care. 2017 Aug;40:213-217. doi: 10.1016/j.jcrc.2017.04.024. Epub 2017 Apr 19.
To compare the ability of a score based on vital signs and laboratory data with that of the modified early warning score (MEWS) to predict ICU transfer of patients with gastrointestinal disorders.
Consecutive events triggering medical emergency team activation in adult patients admitted to the gastroenterology wards of the Asan Medical Center were reviewed. Binary logistic regression was used to identify factors predicting transfer to the ICU. Gastrointestinal early warning score (EWS-GI) was calculated as the sum of simplified regression weights (SRW).
Of the 1219 included patients, 468 (38%) were transferred to the ICU. Multivariate analysis identified heart rate≥105bpm (SRW 1), respiratory rate≥26bpm (SRW 2), ACDU (Alert, Confused, Drowsy, Unresponsive) score≥1 (SRW 2), SpO/FiO ratio<240 (SRW 2), creatinine ≥2.0mg/dL (SRW 2), total bilirubin ≥9.0mg/dL (SRW 2), prothrombin time/international normalized ratio (INR) ≥1.5 (SRW 2), and lactate ≥3.0mmol/L (SRW 2) for inclusion in EWS-GI. The area under the receiver operating characteristic curve of the EWS-GI was larger than that of MEWS (0.76 vs. 0.64; P<0.001).
EWS-GI may predict ICU transfer among patients admitted to gastroenterology wards. The EWS-GI should be prospectively validated.
比较基于生命体征和实验室数据的评分与改良早期预警评分(MEWS)预测胃肠道疾病患者转入重症监护病房(ICU)的能力。
回顾了在峨山医疗中心胃肠病科住院的成年患者中触发医疗急救团队激活的连续事件。采用二元逻辑回归分析来确定预测转入ICU的因素。胃肠道早期预警评分(EWS-GI)通过简化回归权重(SRW)之和计算得出。
在纳入研究的1219例患者中,468例(38%)转入了ICU。多因素分析确定心率≥105次/分钟(SRW 1)、呼吸频率≥26次/分钟(SRW 2)、ACDU(清醒、困惑、嗜睡、无反应)评分≥1(SRW 2)、氧合指数(SpO/FiO)<240(SRW 2)、肌酐≥2.0mg/dL(SRW 2)、总胆红素≥9.0mg/dL(SRW 2)、凝血酶原时间/国际标准化比值(INR)≥1.5(SRW 2)以及乳酸≥3.0mmol/L(SRW 2)纳入EWS-GI。EWS-GI的受试者工作特征曲线下面积大于MEWS(0.76对0.64;P<0.001)。
EWS-GI可能预测胃肠病科病房患者转入ICU的情况。EWS-GI应进行前瞻性验证。