Ritchie Christine L, Pollak Kathryn I, Kehl Karen A, Miller Jeri L, Kutner Jean S
1 Department of Medicine, University of California San Francisco , San Francisco, California.
2 Department of Family Medicine, Duke University , Durham, North Carolina.
J Palliat Med. 2017 Jun;20(6):584-591. doi: 10.1089/jpm.2017.0138. Epub 2017 Apr 27.
To describe the growth and outcomes of the Palliative Care Research Cooperative Group (PCRC).
Despite advances, significant gaps remain in the evidence base to inform care for people with serious illness. To generate this needed evidence and bolster research capacity, the Palliative Care Research Cooperative (PCRC) group was formed.
The PCRC supports investigators in the conduct of multisite clinical studies. After developing a governance structure and completing a proof of concept demonstration study, the PCRC expanded its infrastructure to include additional resource cores (Clinical Studies; Measurement; Data Informatics and Statistics; and Caregiver Studies). The PCRC also supports an Investigator Development Center as many palliative care investigators valued opportunities to advance their skills. Additional key aspects of PCRC resources include a Scientific Review Committee, a Publications Committee, and initiatives to purposefully engage investigators in a community of palliative care science.
The PCRC has grown to over 300 members representing more than 130 distinct sites. To date, the PCRC has supported the submission of 51 research applications and has engaged in 27 studies. The PCRC supports investigator research development needs through webinars and clinical trials "intensives." To foster a sense of community, the PCRC has convened biannual meetings, developed special interest groups, and regularly communicates via a newsletter and its website.
With a particular focus on facilitating conduct of rigorous multisite clinical studies, the PCRC fosters an engaged multidisciplinary research community, filling an important void in generating and disseminating evidence that informs the provision of high-quality care to people with serious illness.
描述姑息治疗研究合作组（PCRC）的发展情况及成果。
尽管取得了进展，但在为重症患者提供护理的证据基础方面仍存在重大差距。为了产生所需的证据并增强研究能力，成立了姑息治疗研究合作组（PCRC）。
PCRC支持研究人员开展多中心临床研究。在建立治理结构并完成概念验证示范研究后，PCRC扩展了其基础设施，增加了其他资源核心（临床研究；测量；数据信息学与统计学；以及照护者研究）。PCRC还支持一个研究人员发展中心，因为许多姑息治疗研究人员重视提升技能的机会。PCRC资源的其他关键方面包括一个科学审查委员会、一个出版委员会，以及旨在让研究人员有目的地融入姑息治疗科学共同体的举措。
PCRC已发展到300多名成员，代表130多个不同的地点。迄今为止，PCRC已支持提交了51项研究申请，并参与了27项研究。PCRC通过网络研讨会和临床试验“强化培训”来支持研究人员的研究发展需求。为了营造共同体意识，PCRC每两年召开一次会议，成立了特别兴趣小组，并通过时事通讯及其网站定期进行沟通。
PCRC特别注重促进开展严谨的多中心临床研究，培育了一个积极参与的多学科研究共同体，填补了在生成和传播为重症患者提供高质量护理的证据方面的重要空白。
