Sánchez-Borges Mario, Fernandez-Caldas Enrique, Thomas Wayne R, Chapman Martin D, Lee Bee Wah, Caraballo Luis, Acevedo Nathalie, Chew Fook Tim, Ansotegui Ignacio J, Behrooz Leili, Phipatanakul Wanda, Gerth van Wijk Roy, Pascal Demoly, Rosario Nelson, Ebisawa Motohiro, Geller Mario, Quirce Santiago, Vrtala Susanne, Valenta Rudolf, Ollert Markus, Canonica Giorgio Walter, Calderón Moises A, Barnes Charles S, Custovic Adnan, Benjaponpitak Suwat, Capriles-Hulett Arnaldo
Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Clínica El Avila, 6ª transversal Urb. Altamira, Piso 8, Consultoria 803, Caracas, 1060 Venezuela.
World Allergy Organ J. 2017 Apr 18;10(1):14. doi: 10.1186/s40413-017-0145-4. eCollection 2017.
Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), the European Academy of Allergy and Clinical Immunology (EAACI), and the World Allergy Organization (WAO), has proposed to issue an International Consensus (ICON) on the clinical consequences of mite hypersensitivity. The objectives of this document are to highlight aspects of mite biology that are clinically relevant, to update the current knowledge on mite allergens, routes of sensitization, the genetics of IgE responses to mites, the epidemiologic aspects of mite hypersensitivity, the clinical pictures induced by mites, the diagnosis, specific immunotherapeutic approaches, and prevention.
由于螨过敏原是全球过敏性疾病最主要的诱发因素，导致了严重的发病率并增加了卫生服务负担，由美国过敏、哮喘与免疫学会（AAAAI）、美国过敏、哮喘与免疫学院（ACAAI）、欧洲过敏与临床免疫学会（EAACI）和世界过敏组织（WAO）组成的国际哮喘、过敏与免疫学协作组织（iCAALL）提议发布一份关于螨超敏反应临床后果的国际共识（ICON）。本文档的目的是强调螨生物学中与临床相关的方面，更新关于螨过敏原、致敏途径、对螨IgE反应的遗传学、螨超敏反应的流行病学方面、螨诱发的临床症状、诊断、特异性免疫治疗方法以及预防的现有知识。
