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心理感觉唤醒驱动力——一种用于小憩及其他常见睡眠-觉醒现象的能量来源:一项假说。

The psycho-sensory wake drive-a power source for power naps and other common sleep-wake phenomena: a hypothesis.

作者信息

George Peter T

机构信息

, 1649 Kalakaua Ave, Suite 204, Honolulu, HI, 96826, USA.

出版信息

Sleep Breath. 2018 Mar;22(1):41-48. doi: 10.1007/s11325-017-1505-6. Epub 2017 Apr 29.

Abstract

Power naps are extensively practiced worldwide and there exists ample documentation of their efficacy in reversing daytime sleepiness. The source of their efficacy, however, as well as the cause and manifestation of many other common sleep-wake phenomena, cannot be entirely explained by the most commonly accepted model of sleep-wake regulation, the two-process model of Borbély, which considers the drives of the circadian and homeostatic sleep processes only. When considering the causes and manifestations of these unexplained phenomena, there appears to be evidence of a wake-promoting drive that is independent of the circadian oscillator indicated in the two-process model of sleep-wake regulation. Although this posited secondary wake drive, herein referred to as the psycho-sensory wake drive, is always active during the awake state, its strength unpredictably varies during a normal day and, therefore, cannot be incorporated into the prevalent two-process model by any current mathematical formula. However, a supplemental graphic model superimposing it on the drives of Process S and Process C can provides plausible and parsimonious explanations for many otherwise unexplainable sleep-wake phenomena and enables rational guidelines for their effective practical management.

摘要

高效短睡眠在全球范围内广泛存在,并且有大量文献证明其在缓解日间嗜睡方面的功效。然而,其功效的来源以及许多其他常见睡眠 - 觉醒现象的原因和表现,无法完全用最普遍接受的睡眠 - 觉醒调节模型——博尔贝利的双过程模型来解释,该模型仅考虑昼夜节律和稳态睡眠过程的驱动因素。在考虑这些无法解释的现象的原因和表现时,似乎有证据表明存在一种促进觉醒的驱动力,它独立于睡眠 - 觉醒调节双过程模型中所指出的昼夜节律振荡器。尽管这种假定的次级觉醒驱动力,在此称为心理 - 感觉觉醒驱动力,在清醒状态下始终处于活跃状态,但其强度在正常一天中会不可预测地变化,因此,任何当前的数学公式都无法将其纳入普遍的双过程模型。然而,一个将其叠加在S过程和C过程驱动力上的补充图形模型,可以为许多原本无法解释的睡眠 - 觉醒现象提供合理且简洁的解释,并为其有效的实际管理提供合理的指导方针。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9612/5835054/8c8029dead7a/11325_2017_1505_Fig1_HTML.jpg

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