Sharkas Ghazi Faisal, Arqoub Kamal H, Khader Yousef S, Tarawneh Mohammad R, Nimri Omar F, Al-Zaghal Marwan J, Subih Hadil S
Field Epidemiology Training Program, Non-Communicable Diseases, Ministry of Health, Amman, Jordan.
Jordan Cancer Registry, Ministry of Health, Amman, Jordan.
J Oncol. 2017;2017:3180762. doi: 10.1155/2017/3180762. Epub 2017 Mar 28.
. To estimate the survival rate of colorectal cancer (CRC) and determine its predictors among Jordanian patients who were diagnosed in the period of 2005-2010. . This study was based on Jordan cancer registry. All CRC cases that were registered in cancer registry during 2005-2010 were analyzed using the survival analysis. The last date for follow-up was 1st Oct 2016. . A total of 3005 patients with CRC were registered during 2005-2010. The overall 5-year and 10-year survival rates for patients with CRC were 58.2% and 51.8%, respectively. The 5-year survival rate decreased significantly from 60.4% for the age <50 years to 49.3% for the age ≥70 years ( < 0.005). The 5-year survival rate was 72.1% for the localized stage, 53.8% for the regional stage, and 22.6% for the distant metastasis. In the multivariate analysis, the only factors that were significantly associated with survival were age, grade, stage, and location of tumor. . The overall 5-year and ten-year survival rates for CRC were 58.2% and 51.8%, respectively. Increased age, poor differentiation, advanced cancer stage, and right-sided cancers were associated with lower survival rates. Screening strategies are needed for early detection of colon adenomas and colorectal cancer in Jordan.
评估约旦2005年至2010年期间确诊的结直肠癌（CRC）患者的生存率，并确定其预测因素。
本研究基于约旦癌症登记处。对2005年至2010年期间癌症登记处登记的所有CRC病例进行生存分析。随访截止日期为2016年10月1日。
2005年至2010年期间共登记了3005例CRC患者。CRC患者的总体5年和10年生存率分别为58.2%和51.8%。5年生存率从年龄<50岁的60.4%显著下降至年龄≥70岁的49.3%（P<0.005）。局限性阶段的5年生存率为72.1%，区域阶段为53.8%，远处转移为22.6%。在多变量分析中，与生存显著相关的唯一因素是年龄、分级、阶段和肿瘤位置。
CRC的总体5年和10年生存率分别为58.2%和51.8%。年龄增加、分化差、癌症晚期和右侧癌症与较低的生存率相关。约旦需要筛查策略以早期发现结肠腺瘤和结直肠癌。
