Hammond William A, Swaika Abhisek, Menke David, Tun Han W
Division of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, USA.
Division of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL, USA.
Rare Tumors. 2017 Mar 28;9(1):6518. doi: 10.4081/rt.2017.6518. eCollection 2017 Mar 24.
Hairy cell leukemia (HCL) is a low grade B-cell lymphoproliferative disorder that typically presents with splenomegaly, cytopenias, and diffuse bone marrow infiltration. There have been few cases in the literature of HCL presenting as lymphomas in extra-nodal locations, such as soft tissues and bones without circulating leukemic cells, splenomegaly, or iliac crest bone marrow involvement. We present an additional case presenting as a thoracic mass, and discuss potential diagnostic pitfalls and management of these rare cases.
毛细胞白血病(HCL)是一种低度B细胞淋巴增殖性疾病,通常表现为脾肿大、血细胞减少和弥漫性骨髓浸润。文献中很少有HCL表现为结外部位淋巴瘤的病例,如软组织和骨骼,无循环白血病细胞、脾肿大或髂嵴骨髓受累。我们报告了一例表现为胸部肿块的病例,并讨论了这些罕见病例的潜在诊断陷阱和治疗方法。