Bahrami Abdollah, Khaleghi Ebrahim, Vakilzadeh Ali Khorsand, Afzalaghaee Monavar
Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Organ Transplant, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Electron Physician. 2017 Feb 25;9(2):3797-3802. doi: 10.19082/3797. eCollection 2017 Feb.
Organ transplantation is the treatment of choice for some diseases. However, the need for cadaveric organ donation has either plateaued or is on a decreasing trend in some countries, especially in developed ones. In this study, we aimed to identify the barriers to organ donation in brain dead patients, who were referred to the organ procurement organizations (OPO) in northeast Iran.
In this cross-sectional study during 2006 to 2013, data were collected from medical records of brain dead patients. Demographic information, cause of brain death, the process of obtaining informed consent, and the reasons for declining organ donation were obtained from the OPO records. The data were analyzed using chi-square test by SPSS 13 software.
Of 1034 brain dead patients, 751 cases (72.6%) were eligible for organ donation, and, ultimately, 344 cases underwent organ donation. The rate of organ donation increased during the course of the study; medical and legal reasons as well as family refusal to authorize donation were the main barriers to the process.
Based on the pattern of mortality, the need for living donors in developing countries, such as Iran and other countries in the Mediterranean region, can be reduced by improving the quality of healthcare, efficient identification of brain death, and obtaining consent with appropriate strategies.
器官移植是某些疾病的首选治疗方法。然而，在一些国家，尤其是发达国家，尸体器官捐赠的需求已趋于平稳或呈下降趋势。在本研究中，我们旨在确定转诊至伊朗东北部器官获取组织（OPO）的脑死亡患者器官捐赠的障碍。
在这项2006年至2013年的横断面研究中，从脑死亡患者的医疗记录中收集数据。人口统计学信息、脑死亡原因、获得知情同意的过程以及拒绝器官捐赠的原因均来自OPO记录。使用SPSS 13软件通过卡方检验对数据进行分析。
在1034例脑死亡患者中，751例（72.6%）符合器官捐赠条件，最终344例接受了器官捐赠。在研究过程中器官捐赠率有所上升；医疗和法律原因以及家属拒绝授权捐赠是该过程的主要障碍。
根据死亡率模式，通过提高医疗质量、有效识别脑死亡以及采用适当策略获得同意，可以减少伊朗和地中海地区其他国家等发展中国家对活体捐赠者的需求。
