Soliman Ashraf T, De Sanctis Vincenzo, Yassin Mohamed, Soliman Nada
Department of Pediatrics, Alexandria University Children Hospital, Elchatby, Alexandria, Egypt.
Acta Biomed. 2017 Apr 28;88(1):112-118. doi: 10.23750/abm.v88i1.6049.
Iron deficiency anemia (IDA) is a global public health problem affecting both developing and developed countries with major consequences for human health as well as social and economic development. It occurs at all stages of the life cycle, but is more prevalent in pregnant women and young children. IDA appears to be more common in diabetic patients compared to non-diabetic population. Iron deficiency (ID) and IDA can impair glucose homeostasis in animals and human and may negatively affect glycemic control and predispose to more complications in diabetic patients. On the other hand diabetes and its complications are associated with anemia and its correction improves diabetes control and may prevent or delay the occurrence of complications. Physicians treating this form of anemia should be aware of its negative effect on glycemic control in normal and diabetic patients (both type 1 and type 2). They should prevent ID and treat early all those with IDA.This brief review aims to enlighten the different effects of IDA on glucose metabolism in normal and diabetic patients.
缺铁性贫血(IDA)是一个全球性的公共卫生问题,影响着发展中国家和发达国家,对人类健康以及社会和经济发展都有重大影响。它发生在生命周期的各个阶段,但在孕妇和幼儿中更为普遍。与非糖尿病人群相比,IDA在糖尿病患者中似乎更为常见。缺铁(ID)和IDA会损害动物和人类的葡萄糖稳态,并可能对血糖控制产生负面影响,使糖尿病患者更容易出现更多并发症。另一方面,糖尿病及其并发症与贫血有关,纠正贫血可改善糖尿病控制,并可能预防或延缓并发症的发生。治疗这种贫血形式的医生应该意识到它对正常和糖尿病患者(1型和2型)血糖控制的负面影响。他们应该预防ID,并尽早治疗所有IDA患者。本简要综述旨在阐明IDA对正常和糖尿病患者葡萄糖代谢的不同影响。