Resnik David B
Dev World Bioeth. 2018 Jun;18(2):135-143. doi: 10.1111/dewb.12147. Epub 2017 May 3.
Effective community engagement is an important legal, ethical, and practical prerequisite for conducting field trials of genetically modified mosquitoes, because these studies can substantially impact communities and it is usually not possible to obtain informed consent from each community member. Researchers who are planning to conduct field trials should develop a robust community engagement strategy that meets widely recognized standards for seeking approval from the affected population, such as timeliness, consent, information sharing, transparency, understanding, responsiveness, mutual understanding, inclusiveness, and respectfulness. Additional research is needed on the effectiveness of different methods of engaging communities in field trials of genetically modified mosquitoes and how to respond to public opposition to genetically modified organisms. For research programs involving the genetic modification of disease vectors to move forward, they must have public acceptance and support, which cannot be achieved without effective community engagement.
有效的社区参与是开展转基因蚊子实地试验的重要法律、伦理和实际前提，因为这些研究可能对社区产生重大影响，而且通常无法获得每个社区成员的知情同意。计划开展实地试验的研究人员应制定强有力的社区参与策略，该策略要符合从受影响人群那里寻求批准的广泛认可标准，如及时性、同意、信息共享、透明度、理解、响应能力、相互理解、包容性和尊重。需要进一步研究不同方法在转基因蚊子实地试验中让社区参与的有效性，以及如何应对公众对转基因生物的反对。对于涉及对病媒进行基因改造的研究项目来说，要想推进，必须获得公众的接受和支持，而没有有效的社区参与就无法实现这一点。
