Early Heather, Aguilera Jorge, Cheang Ellen, McGahan John
Department of Radiology, University of California Davis Medical Center, Sacramento, California, USA.
J Ultrasound Med. 2017 Sep;36(9):1771-1782. doi: 10.1002/jum.14217. Epub 2017 May 4.
The gold standard in evaluating renal allograft dysfunction has traditionally been renal biopsy. However, not only does biopsy come with inherent risks, the time frame from biopsy to detecting renal dysfunction is often inefficient. It is therefore advantageous to have a noninvasive, low-cost, time-saving method, such as shear wave elastography (SWE), to detect fibrosis early, to maximize immunosuppressive care. It is important to consider factors that affect tissue stiffness in the kidney, as well as the challenges incurred when using SWE in this anisotropic organ, in order to select the most appropriate patients for this exam.
传统上，评估肾移植功能障碍的金标准一直是肾活检。然而，活检不仅存在固有风险，而且从活检到检测出肾功能障碍的时间框架往往效率低下。因此，拥有一种非侵入性、低成本、节省时间的方法，如剪切波弹性成像（SWE），以便早期检测纤维化，从而最大限度地优化免疫抑制治疗，是很有优势的。为了选择最适合进行这项检查的患者，考虑影响肾脏组织硬度的因素以及在这个各向异性器官中使用SWE时所面临的挑战非常重要。
