Mi Yue, Zhang Jinrong, He Shan, Yan Xiaojun
School of Marine Sciences, Laboratory of Marine Natural Products, Ningbo University, Ningbo 315211, China.
Key Laboratory of Applied Marine Biotechnology of Ministry of Education, Ningbo University, Ningbo 315211, China.
Mar Drugs. 2017 May 5;15(5):132. doi: 10.3390/md15050132.
Marine cyanobacteria are significant sources of structurally diverse marine natural products with broad biological activities. In the past 10 years, excellent progress has been made in the discovery of marine cyanobacteria-derived peptides with diverse chemical structures. Most of these peptides exhibit strong pharmacological activities, such as neurotoxicity and cytotoxicity. In the present review, we summarized peptides isolated from marine cyanobacteria since 2007.
海洋蓝细菌是具有广泛生物活性的结构多样的海洋天然产物的重要来源。在过去十年中,在发现具有不同化学结构的海洋蓝细菌衍生肽方面取得了显著进展。这些肽大多具有强大的药理活性,如神经毒性和细胞毒性。在本综述中,我们总结了自2007年以来从海洋蓝细菌中分离出的肽。