Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania - Luigi Vanvitelli, Naples, Italy.
J Oral Pathol Med. 2017 Nov;46(10):864-876. doi: 10.1111/jop.12589. Epub 2017 May 30.
The introduction of optical coherence tomography (OCT) in dentistry enabled the integration of already existing clinical and laboratory investigations in the study of the oral cavity. This systematic review presents an overview of the literature, to evaluate the usefulness of in vivo OCT for diagnosing oral soft tissues lesions, to compare the OCT results with traditional histology, and to identify limitations in prior studies so as to improve OCT applications.
We performed a review of the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library) employing MeSH terms such as "optical coherence tomography" and "OCT" in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria.
Initial results were 3155. In conclusion, there were only 27 studies which met our selection criteria. We decided to allocate the 27 selected items into three groups: healthy mucosa; benign, premalignant, and malignant lesions; and oral manifestations of systemic therapies or pathological conditions.
Although the OCT is an easy-to-perform test and it offers an attractive diagnostic and monitoring prospect for soft tissues of the oral cavity, further studies are needed to complete the current knowledge of this imaging technique.
光学相干断层扫描（OCT）在牙科中的引入使得已经存在的临床和实验室研究能够整合到口腔研究中。本系统综述概述了文献，以评估体内 OCT 诊断口腔软组织病变的有用性，将 OCT 结果与传统组织学进行比较，并确定先前研究中的局限性，以改进 OCT 的应用。
我们使用不同的搜索引擎（PubMed、ISI Web of Science 和 Cochrane Library），使用“光学相干断层扫描”和“OCT”等主题词以及其他术语进行了文献回顾。我们利用人群、干预、比较、结果和研究设计（PICOS）方法来定义我们的研究入选标准。
最初的结果是 3155 篇。结论是，只有 27 项研究符合我们的选择标准。我们决定将 27 项选定的项目分为三组：健康黏膜；良性、癌前和恶性病变；以及系统性治疗或病理状况的口腔表现。
尽管 OCT 是一种易于进行的测试，它为口腔软组织提供了有吸引力的诊断和监测前景，但仍需要进一步的研究来完善该成像技术的现有知识。
