Kadkhoda Kamran, Gretchen Ainsley, Racano Adrianna
Cadham Provincial Public Health Laboratory, Winnipeg, MB, Canada; Departments of Medical Microbiology & Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada; Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Cadham Provincial Public Health Laboratory, Winnipeg, MB, Canada.
Diagn Microbiol Infect Dis. 2017 Jul;88(3):233-235. doi: 10.1016/j.diagmicrobio.2017.04.002. Epub 2017 Apr 7.
Zika virus (ZIKV), an emerging arbovirus, has become the center of attention since it was linked to congenital abnormalities. Given the overlapping clinical picture of ZIKV disease with other infectious diseases and as an exigent public health matter, timely and reliable diagnosis of ZIKV infection is crucial. We evaluated the performance of a commercially available NS1-based ZIKV IgM ELISA. Our results showed suboptimal sensitivity within the first 5 days after onset while specificity remained robust.
寨卡病毒（ZIKV）是一种新出现的虫媒病毒，自它与先天性异常有关联以来，已成为人们关注的焦点。鉴于寨卡病毒病与其他传染病的临床表现重叠，且作为一个紧急的公共卫生问题，对寨卡病毒感染进行及时、可靠的诊断至关重要。我们评估了一种市售的基于NS1的寨卡病毒IgM酶联免疫吸附测定（ELISA）的性能。我们的结果显示，发病后头5天内敏感性欠佳，而特异性仍然很强。
