University of California, San Diego, United States.
Neuropsychiatric Research Institute, Fargo, ND, United States; University of North Dakota School of Medicine and Health Sciences, United States.
J Psychiatr Res. 2017 Sep;92:183-190. doi: 10.1016/j.jpsychires.2017.04.009. Epub 2017 Apr 26.
Prior research suggests that the construct of emotional instability may be salient to bulimia nervosa (BN), but no study to date has used ecological momentary assessment (EMA) to examine its temporal association with binge eating and purging. In the current study, 133 women with DSM-IV BN used portable digital devices to provide multiple daily negative affect (NA) and positive affect (PA) ratings and record eating disorder behaviors over 2 weeks. Two state-of-the art indices quantified affective instability: probability of acute change (PAC), which represents the likelihood of extreme affective increases, and mean squared successive difference (MSSD), which represents average change over successive recordings. For extreme affective change, results revealed that on bulimic behavior days, extreme NA increases were less likely after bulimic behaviors than before them, and extreme increases in PA were more likely after bulimic behaviors than during the same time period on non-bulimic behavior days. However, average NA instability (i.e., MSSD) was (a) greater on bulimic behavior days than non-bulimic behavior days, (b) greater after bulimic behaviors than during the same time period on non-bulimic behavior days, and (c) greater after bulimic behaviors than before them. Results lend support to the notion that bulimic behaviors are negatively reinforcing (i.e., via post-behavior acute affective changes), but also indicate that these behaviors may exacerbate overall affective dysregulation. These findings may improve understanding of BN maintenance and inform the development of novel interventions or refinement of existing treatments.
先前的研究表明,情绪不稳定的结构可能与神经性贪食症(BN)有关,但迄今为止,没有研究使用生态瞬时评估(EMA)来检查其与暴食和清除行为的时间关联。在目前的研究中,133 名患有 DSM-IV BN 的女性使用便携式数字设备提供了 2 周内多次日常的负面情绪(NA)和正面情绪(PA)评分,并记录了饮食失调行为。两个最先进的指标量化了情感不稳定:急性变化概率(PAC),代表极端情感增加的可能性,以及均方连续差异(MSSD),代表连续记录中的平均变化。对于极端情感变化,结果表明,在暴食行为日,暴食行为后极端 NA 增加的可能性小于暴食行为前,而暴食行为后极端 PA 增加的可能性大于非暴食行为日的同一时间。然而,平均 NA 不稳定性(即 MSSD)(a)在暴食行为日大于非暴食行为日,(b)在暴食行为后大于非暴食行为日的同一时间,(c)在暴食行为后大于暴食行为前。研究结果支持这样一种观点,即暴食行为具有负向强化作用(即通过行为后急性情感变化),但也表明这些行为可能会加剧整体情感失调。这些发现可能有助于更好地理解 BN 的维持,并为新的干预措施的发展或现有治疗方法的改进提供信息。