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健康超重志愿者每日食用三苏拉方与改善血脂水平的关系:一项开放标签、随机对照试验

Improved Lipid Profile Associated with Daily Consumption of Tri-Sura-Phon in Healthy Overweight Volunteers: An Open-Label, Randomized Controlled Trial.

作者信息

Kuamsub Sirigoon, Singthong Pariyaphat, Chanthasri Wipawee, Chobngam Nicharee, Sangkaew Warissara, Hemdecho Sasithorn, Kaewmanee Thammarat, Chusri Sasitorn

机构信息

Natural Product Research Center of Excellence and Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

Faculty of Thai Traditional and Alternative Medicine, Ubonratchathani Rajabhat University, Meung, Ubonratchathani 34000, Thailand.

出版信息

Evid Based Complement Alternat Med. 2017;2017:2687173. doi: 10.1155/2017/2687173. Epub 2017 Apr 6.

DOI:10.1155/2017/2687173
PMID:28484502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5397647/
Abstract

Tri-Sura-Phon (TSP), a traditional Thai polyherbal formula renowned for its rejuvenating properties, is commonly used as a blood tonic. It comprises , , and . The aim of this study is to evaluate the beneficial properties of TSP tea consumption on blood glucose regulation and serum lipid profiles of healthy overweight volunteers. This open-label, randomized controlled trial was conducted in 70 healthy overweight adults. Two groups of 35 subjects took a TSP infusion or a placebo (cornstarch) twice daily for 8 weeks. The blood glucose regulation, serum lipid profiles, BMI, and liver function tests of the subjects were determined at the baseline, 4th week, and endpoint (8th week). Significant decreases in the average fasting levels of total cholesterol ( = 0.013), triglyceride ( = 0.001), and low-density lipoprotein (LDL, = 0.017) were observed in the TSP group at the 8th week compared to those at the baseline. The average HDL level in the TSP group at the beginning of the study was 65.2 mg/dL, and it increased significantly ( = 0.005) to 72.4 mg/dL after 8 weeks of TSP intake. This study showed that the intake of TSP tea as an antioxidant-rich beverage might be safe and improve lipid profiles in overweight adults.

摘要

三苏罗芬(TSP)是一种以其回春功效而闻名的传统泰国多草药配方,通常用作补血剂。它由[此处原文缺失具体成分]组成。本研究的目的是评估饮用TSP茶对健康超重志愿者血糖调节和血脂谱的有益特性。这项开放标签、随机对照试验在70名健康超重成年人中进行。两组各35名受试者每天服用两次TSP冲泡剂或安慰剂(玉米淀粉),持续8周。在基线、第4周和终点(第8周)测定受试者的血糖调节、血脂谱、BMI和肝功能测试。与基线相比,TSP组在第8周时总胆固醇(P = 0.013)、甘油三酯(P = 0.001)和低密度脂蛋白(LDL,P = 0.017)的平均空腹水平显著降低。TSP组在研究开始时的平均高密度脂蛋白水平为65.2毫克/分升,在摄入TSP 8周后显著升高(P = 0.005)至72.4毫克/分升。这项研究表明,将TSP茶作为富含抗氧化剂的饮料饮用可能对超重成年人是安全的,并能改善血脂谱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4d/5397647/8d61ae0690bb/ECAM2017-2687173.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4d/5397647/01f31ba6fda6/ECAM2017-2687173.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4d/5397647/8d61ae0690bb/ECAM2017-2687173.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4d/5397647/01f31ba6fda6/ECAM2017-2687173.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4d/5397647/8d61ae0690bb/ECAM2017-2687173.002.jpg

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