Pradeep A R, Suke Deepak Kumar, Martande Santosh S, Singh Sonender Pal, Nagpal Kanika, Naik Savitha B
Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka, India.
Department of Periodontology and Oral Implantology, Dr. D.Y. Patil Dental College and Hospital, Pimpri, Pune, Mahrashtra, India.
J Periodontol. 2016 Nov;87(11):1352-1359. doi: 10.1902/jop.2016.130406. Epub 2016 Jul 21.
An antiplaque agent with minimal side effects that can be used as an effective adjunct to mechanical plaque control is needed. The current study is designed to evaluate efficacy of triphala (TRP) mouthwash in reduction of plaque and gingivitis.
Ninety individuals with chronic generalized gingivitis were randomly assigned to three groups: 1) group I, placebo mouthwash; 2) group II, TRP mouthwash; and 3) group III, chlorhexidine (CHX) mouthwash. All individuals were instructed to rinse with their respective mouthwash twice daily. 1) Plaque index (PI); 2) gingival index (GI); 3) oral hygiene index-simplified (OHI-S); and 4) microbiologic colony counts were recorded at baseline and at 7, 30, and 60 days.
All three groups showed gradual reduction in PI, GI, and OHI-S levels from baseline to 7, 30, and 60 days. There was also significant reduction in microbial counts in all groups at all time intervals except in group I. A significant difference was noticed with respect to reduction in PI, GI, OHI-S, and microbiologic counts in group I compared with groups II and III. However, no significant differences were found between groups II and III for any parameters at any time intervals.
TRP mouthwash was found to decrease inflammatory parameters from baseline to follow-up intervals. Because improvement in gingivitis was comparable with that of CHX mouthwash, TRP mouthwash can be considered a potential therapeutic agent in the treatment of gingivitis.
需要一种副作用最小的抗牙菌斑剂，可作为机械性牙菌斑控制的有效辅助手段。本研究旨在评估三果口漱液（TRP）在减少牙菌斑和牙龈炎方面的疗效。
90名患有慢性广泛性牙龈炎的个体被随机分为三组：1）第一组，安慰剂口漱液；2）第二组，TRP口漱液；3）第三组，氯己定（CHX）口漱液。所有个体均被指示每天用各自的口漱液漱口两次。在基线、第7天、第30天和第60天记录：1）菌斑指数（PI）；2）牙龈指数（GI）；3）简化口腔卫生指数（OHI-S）；4）微生物菌落计数。
从基线到第7天、第30天和第60天，所有三组的PI、GI和OHI-S水平均逐渐降低。除第一组外，所有组在所有时间间隔的微生物计数也均显著降低。与第二组和第三组相比，第一组在PI、GI、OHI-S和微生物计数的降低方面存在显著差异。然而，在任何时间间隔，第二组和第三组之间的任何参数均未发现显著差异。
发现TRP口漱液可使从基线到随访间隔的炎症参数降低。由于牙龈炎的改善与CHX口漱液相当，TRP口漱液可被视为治疗牙龈炎的一种潜在治疗剂。
