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协助寨卡病毒传播

ADE-ing and Abetting Zika.

作者信息

Wen Jinsheng, Shresta Sujan

机构信息

Division of Inflammation Biology, La Jolla Institute for Allergy & Immunology, La Jolla, CA 92037, USA; Institute of Arboviruses, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.

Division of Inflammation Biology, La Jolla Institute for Allergy & Immunology, La Jolla, CA 92037, USA.

出版信息

Cell Host Microbe. 2017 May 10;21(5):557-558. doi: 10.1016/j.chom.2017.04.006.

DOI:10.1016/j.chom.2017.04.006
PMID:28494235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5808914/
Abstract

Although dengue virus (DENV) antibodies can neutralize or enhance Zika virus (ZIKV) infection in vitro, their contribution to ZIKV infection in vivo remains unclear. In a recent issue of Science, Bardina et al. (2017) explore the protective versus pathogenic roles of DENV-immune antibodies in ZIKV infection using a mouse model.

摘要

尽管登革热病毒（DENV）抗体在体外能够中和或增强寨卡病毒（ZIKV）感染，但其在体内对ZIKV感染的作用仍不清楚。在最近一期的《科学》杂志上，巴尔迪纳等人（2017年）使用小鼠模型探讨了DENV免疫抗体在ZIKV感染中的保护作用与致病作用。

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ADE-ing and Abetting Zika.协助寨卡病毒传播
Cell Host Microbe. 2017 May 10;21(5):557-558. doi: 10.1016/j.chom.2017.04.006.
2
Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.母体获得的寨卡抗体增强了小鼠登革热的严重程度。
Cell Host Microbe. 2018 Nov 14;24(5):743-750.e5. doi: 10.1016/j.chom.2018.09.015.
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Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice.登革热病毒和寨卡病毒血清学交叉反应及其对小鼠发病机制的影响。
J Infect Dis. 2019 Jan 7;219(2):223-233. doi: 10.1093/infdis/jiy482.
4
Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection.抗体依赖性增强作用对登革热/寨卡病毒致病性的调节作用及寨卡病毒感染中预防增强作用的策略。
Front Immunol. 2018 Apr 23;9:597. doi: 10.3389/fimmu.2018.00597. eCollection 2018.
5
Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models.登革热和 Zika 病毒感染可被减毒活疫苗增强，但在小鼠模型中，重组 DSV4 候选疫苗不会增强登革热感染。
EBioMedicine. 2020 Oct;60:102991. doi: 10.1016/j.ebiom.2020.102991. Epub 2020 Sep 16.
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Dengue and Zika Virus Domain III-Flagellin Fusion and Glycan-Masking E Antigen for Prime-Boost Immunization.登革热和 Zika 病毒结构域 III-鞭毛蛋白融合和糖基掩蔽 E 抗原用于初次-加强免疫。
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Cross-Reactive Flavivirus Antibody: Friend and Foe?交叉反应性黄病毒抗体：是敌是友？
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Zika convalescent macaques display delayed induction of anamnestic cross-neutralizing antibody responses after dengue infection. Zika 恢复期猕猴在登革热感染后表现出迟发性回忆性中和抗体反应的诱导。
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Dengue immune sera enhance Zika virus infection in human peripheral blood monocytes through Fc gamma receptors.登革热免疫血清通过 Fcγ 受体增强 Zika 病毒在人外周血单核细胞中的感染。
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EDIII-Fc induces protective immune responses against the Zika virus in mice and rhesus macaque.EDIII-Fc 诱导小鼠和恒河猴对寨卡病毒产生保护性免疫应答。
PLoS Negl Trop Dis. 2023 Nov 20;17(11):e0011770. doi: 10.1371/journal.pntd.0011770. eCollection 2023 Nov.
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Omicron (B.1.1.529) BA.1 or BA.2-related effects on immune responses in previously naïve versus imprinted individuals: immune imprinting as an advantage in the humoral immune response against novel variants.

本文引用的文献

1
Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity.既往抗黄病毒免疫增强寨卡病毒致病性
Science. 2017 Apr 14;356(6334):175-180. doi: 10.1126/science.aal4365. Epub 2017 Mar 30.
2
Modified mRNA Vaccines Protect against Zika Virus Infection.改良型mRNA疫苗可预防寨卡病毒感染。
Cell. 2017 Mar 23;169(1):176. doi: 10.1016/j.cell.2017.03.016.
3
Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8 T cells.鉴定寨卡病毒表位揭示了登革热病毒交叉反应性 CD8 T 细胞的免疫优势和保护作用。
奥密克戎（B.1.1.529）BA.1 或 BA.2 相关的对既往无记忆和有记忆个体免疫应答的影响：免疫印迹作为针对新型变异体的体液免疫应答优势。
Front Immunol. 2023 May 15;14:1165769. doi: 10.3389/fimmu.2023.1165769. eCollection 2023.
Nat Microbiol. 2017 Mar 13;2:17036. doi: 10.1038/nmicrobiol.2017.36.
4
Mapping and Role of the CD8 T Cell Response During Primary Zika Virus Infection in Mice.小鼠初次感染寨卡病毒期间CD8 T细胞反应的图谱及作用
Cell Host Microbe. 2017 Jan 11;21(1):35-46. doi: 10.1016/j.chom.2016.12.010.
5
Immunogenic cross-talk between dengue and Zika viruses.登革热病毒与寨卡病毒之间的免疫原性相互作用。
Nat Immunol. 2016 Aug 19;17(9):1010-2. doi: 10.1038/ni.3539.
6
Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus.登革病毒血清交叉反应性驱动寨卡病毒感染的抗体依赖性增强。
Nat Immunol. 2016 Sep;17(9):1102-8. doi: 10.1038/ni.3515. Epub 2016 Jun 23.
7
The global distribution and burden of dengue.登革热的全球分布和负担。
Nature. 2013 Apr 25;496(7446):504-7. doi: 10.1038/nature12060. Epub 2013 Apr 7.
8
Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification.Fc 修饰可防止登革热疾病在小鼠中的致命抗体增强。
PLoS Pathog. 2010 Feb 12;6(2):e1000790. doi: 10.1371/journal.ppat.1000790.
9
Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease.抗体诱导的重症登革热疾病小鼠模型中肝窦内皮细胞的易感性增强。
Cell Host Microbe. 2010 Feb 18;7(2):128-39. doi: 10.1016/j.chom.2010.01.004.
10
Dengue.登革热
Lancet. 2007 Nov 10;370(9599):1644-52. doi: 10.1016/S0140-6736(07)61687-0.