Balasubramanian Siva, Uji Akihito, Lei Jianqin, Velaga Swetha, Nittala Muneeswar, Sadda SriniVas
Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, California.
Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California.
Br J Ophthalmol. 2018 Jan;102(1):109-113. doi: 10.1136/bjophthalmol-2017-310258. Epub 2017 May 11.
To compare and correlate the retinal sensitivity measurements obtained with Nidek Microperimetry-3 (MP-3) and the CenterVue Macular Integrity Assessment (MAIA) microperimeters among healthy subjects.
In this prospective comparative study, 31 eyes of 23 subjects underwent complete ophthalmological examination including retinal sensitivity assessments using two microperimeters, the MP-3 (Nidek Technologies) and the MAIA (CenterVue). The mean retinal sensitivity (dB) and its corresponding luminance (asb) and contrast (log units) were analysed between the two instruments. The interdevice reproducibility and level of agreement between the sensitivity values of the devices were assessed.
The mean retinal sensitivity (dB) measured by the MP-3 (25.02±1.06 dB, range: 20.90-26.70) was significantly (p<0.0001) lower compared with the MAIA (30.68±0.74 dB, range: 28-31.84). The luminosity levels were significantly (p<0.0001) higher with the MP3 (7.75±1.31 asb, range: 6.44-9.06) compared with the MAIA (0.92±0.14 asb, range: 0.78-1.06). The contrast sensitivity was significantly higher for the MP-3 (0.94±0.33 log units, range: 0.61-1.27) compared with the MAIA (0.23±0.03 log units, range: 0.20-0.26). Despite these absolute differences, the intraclass coefficient was 0.85 (95% CI 0.70 to 0.92) between the two devices after applying a standard correction factor to each data point (MAIA sensitivity=MP-3 sensitivity+5.65) with a mean difference between MAIA and MP-3 of 0.01.
Retinal sensitivity measures higher, but luminance and contrast sensitivity measure lower for MAIA-generated values compared with the MP-3. The relationships, however, appeared fairly consistent, and application of a standard correction factor allowed the data to be inter-related, at least for normal eyes.
比较并关联健康受试者使用尼德克Microperimetry-3（MP-3）和CenterVue黄斑完整性评估（MAIA）微视野计所获得的视网膜敏感度测量结果。
在这项前瞻性比较研究中，23名受试者的31只眼睛接受了全面的眼科检查，包括使用两种微视野计（MP-3，尼德克科技公司；MAIA，CenterVue）进行视网膜敏感度评估。分析了两种仪器之间的平均视网膜敏感度（dB）及其相应的亮度（asb）和对比度（对数单位）。评估了设备间的可重复性以及设备敏感度值之间的一致性水平。
MP-3测量的平均视网膜敏感度（dB）为（25.02±1.06dB，范围：20.90 - 26.70），与MAIA（30.68±0.74dB，范围：28 - 31.84）相比显著更低（p<0.0001）。MP3的亮度水平（7.75±1.31asb，范围：6.44 - 9.06）与MAIA（0.92±0.14asb，范围：0.78 - 1.06）相比显著更高（p<0.0001）。MP-3的对比度敏感度（0.94±0.33对数单位，范围：0.61 - 1.27）与MAIA（0.23±0.03对数单位，范围：0.20 - 0.26）相比显著更高。尽管存在这些绝对差异，但在对每个数据点应用标准校正因子（MAIA敏感度 = MP-3敏感度 + 5.65）后，两种设备之间的组内系数为0.85（95%CI 0.70至0.92），MAIA和MP-3之间的平均差异为0.01。
与MP-3相比，MAIA生成的值的视网膜敏感度测量值更高，但亮度和对比度敏感度测量值更低。然而，这些关系似乎相当一致，并且应用标准校正因子使得数据能够相互关联，至少对于正常眼睛是这样。
