Molina-Martín Ainhoa, Piñero David P, Pérez-Cambrodí Rafael J
a Clínica Optométrica, Fundació Lluis Alcanyís, Universitat de València , Valencia , Spain .
b Department of Ophthalmology , Oftalmar, Hospital Internacional Medimar , Alicante , Spain , and.
Curr Eye Res. 2016;41(3):400-9. doi: 10.3109/02713683.2015.1020170. Epub 2015 Apr 10.
To evaluate the reliability and intersession agreement of measurements of retinal sensitivity as well as of the fixation pattern obtained in healthy eyes with a microperimeter integrating the mechanism of the scanning laser ophthalmoscope (SLO) with the static perimetry.
This study included a sample of 44 healthy eyes of 44 subjects of a mean age of 27.0 ± 8.5 years. In all cases, microperimetric exams with the MAIA system (Centervue, Padova, Italy) were performed in three different sessions to evaluate the intersession repeatability. The consistency of measurements was analyzed by using the Friedman test and by analyzing the correlation between consecutive measurements. Agreement between the first and third sessions was assessed by using the Passing-Bablok regression analysis. The following parameters were analyzed: average threshold (AT), macular integrity (MI) index, fixation indexes P1 and P2, bivariate contour ellipse area (BCEA), major and minor axes of the ellipse and high preferred retinal locus position (PRLh).
Not statistically significant differences were found in the evaluated parameters between the three sessions (p ≥ 0.193). The correlation between consecutive measurements was moderate to strong for all parameters evaluated (r ≥ 0.49, p < 0.01), except for the MI and the position of the PRLh (r ≤ 0.305, p ≥ 0.05). The Passing-Bablok regression analysis showed a good agreement between the first and third measurement for all parameters, except for the MI and the position of the PRLh.
MAIA MP system is able to provide consistent measurements of AT and fixation in normal subjects. MI and the position of PRLh seem to be the least reliable parameters in this group of patients.
使用一种将扫描激光检眼镜(SLO)的机制与静态视野计相结合的微视野计,评估健康眼睛视网膜敏感度测量以及注视模式测量的可靠性和不同检查之间的一致性。
本研究纳入了44名受试者的44只健康眼睛,受试者平均年龄为27.0 ± 8.5岁。所有病例均使用MAIA系统(意大利帕多瓦Centervue公司)在三个不同时间段进行微视野检查,以评估不同时间段之间的可重复性。通过Friedman检验并分析连续测量之间的相关性来分析测量的一致性。使用Passing-Bablok回归分析评估第一次和第三次检查之间的一致性。分析了以下参数:平均阈值(AT)、黄斑完整性(MI)指数、注视指数P1和P2、双变量轮廓椭圆面积(BCEA)、椭圆的长轴和短轴以及高首选视网膜位点位置(PRLh)。
在三个时间段之间,所评估的参数未发现有统计学意义的差异(p ≥ 0.193)。除MI和PRLh的位置外,所有评估参数的连续测量之间的相关性为中度至高度(r ≥ 0.49,p < 0.01)(r ≤ 0.305,p ≥ 0.05)。Passing-Bablok回归分析显示,除MI和PRLh的位置外,所有参数的第一次和第三次测量之间具有良好的一致性。
MAIA MP系统能够为正常受试者提供一致的AT和注视测量。在这组患者中,MI和PRLh的位置似乎是最不可靠的参数。