Division of Ophthalmology, Laboratory for Investigation in Ophthalmology (LIM-33), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Arq Bras Oftalmol. 2023 Apr 3;87(5):e20210472. doi: 10.5935/0004-2749.2021-0472. eCollection 2023.
Microperimetry has been used for several years as a form of visual function testing in patients with retinal diseases. Normal microperimetry values obtained with microperimeter MP-3 have not yet been fully published, and baseline values for topographic macular sensitivity and correlations with age and sex are needed to establish degrees of impairment. This study aimed to determine values for light sensitivity thresholds and fixation stability using the MP-3 in healthy individuals.
Thirty-seven healthy volunteers (age, 28-68 years), underwent full-threshold microperimetry using a 4-2 (fast) staircase strategy with the standard Goldmann III stimulus size and 68 test points positioned identically to those in the Humphrey Field Analyzer 10-2 test grid. The fixation stability was simultaneously recorded during the microperimetry test. The relationship between global sensitivity and age was calculated using linear regression analysis.
Microperimetry was performed on 37 participants (74 eyes). The global mean sensitivity was 29.01 ± 1.44 (range, 26-31) dB. The mean central sensitivity at 2° measured by the MP-3 was 28.5 ± 1.77 dB in the right eye (OD) and 28.75 ± 1.98 dB in the left eye (OS). The total median fixation stability values within 2° and 4° were 80% and 96%, respectively. The linear regression analysis also revealed an age-related global sensitivity decline per year of -0.051 dB ± 0.018 (OD) and -0.078 dB ± 0.021 (OS).
Microperimetry performed with the MP-3 allows for an automatic, accurate, and topography-specific examination of retinal sensitivity thresholds. The results of this study provide a normal and age-matched database of MP-3 microperimetry.
微视野计已被用于对视网膜疾病患者的视觉功能进行检测多年。使用微视野计 MP-3 获得的正常微视野计值尚未完全公布，需要确定黄斑敏感性的基线值以及与年龄和性别的相关性，以确定损伤程度。本研究旨在确定使用 MP-3 测量健康个体的光敏感度阈值和固视稳定性。
37 名健康志愿者（年龄 28-68 岁）接受了使用 4-2（快速）阶梯策略的全阈值微视野计检查，标准 Goldmann III 刺激大小和 68 个测试点与 Humphrey Field Analyzer 10-2 测试网格中的测试点位置完全相同。在微视野计检查期间同时记录固视稳定性。使用线性回归分析计算全球敏感性与年龄之间的关系。
对 37 名参与者（74 只眼）进行了微视野计检查。平均全局敏感度为 29.01 ± 1.44（范围 26-31）dB。MP-3 测量的 2°中心敏感度在右眼（OD）为 28.5 ± 1.77 dB，左眼（OS）为 28.75 ± 1.98 dB。2°和 4°内的总中位数固视稳定性值分别为 80%和 96%。线性回归分析还显示，全球敏感性每年与年龄相关的下降率为 -0.051 dB ± 0.018（OD）和 -0.078 dB ± 0.021（OS）。
使用 MP-3 进行的微视野计检查可实现视网膜敏感度阈值的自动、准确和特定于地形图的检查。本研究的结果提供了 MP-3 微视野计的正常和年龄匹配的数据库。
