Jacob Louis, Kostev Karel
Faculty of Medicine, University of Paris 5, Paris, France.
Epidemiology, IMS Health, Frankfurt, Germany.
Ger Med Sci. 2017 Apr 26;15:Doc08. doi: 10.3205/000249. eCollection 2017.
Only few authors have analyzed the impact of workplace conflicts and the resulting stress on the risk of developing cardiovascular disorders. The goal of this study was to analyze the association between workplace conflicts and cardiovascular disorders in patients treated by German general practitioners. Patients with an initial documentation of a workplace conflict experience between 2005 and 2014 were identified in 699 general practitioner practices (index date). We included only those who were between the ages of 18 and 65 years, had a follow-up time of at least 180 days after the index date, and had not been diagnosed with angina pectoris, myocardial infarction, coronary heart diseases, or stroke prior to the documentation of the workplace mobbing. In total, the study population consisted of 7,374 patients who experienced conflicts and 7,374 controls for analysis. The main outcome measure was the incidence of angina pectoris, myocardial infarction, and stroke correlated with workplace conflict experiences. After a maximum of five years of follow-up, 2.9% of individuals who experienced workplace conflict were affected by cardiovascular diseases, while only 1.4% were affected in the control group (p-value <0.001). Workplace conflict was associated with a 1.63-fold increase in the risk of developing cardiovascular diseases. Finally, the impact of workplace conflict was higher for myocardial infarction (OR=2.03) than for angina pectoris (OR=1.79) and stroke (OR=1.56). Overall, we found a significant association between workplace conflicts and cardiovascular disorders.
只有少数作者分析过职场冲突及其引发的压力对患心血管疾病风险的影响。本研究的目的是分析德国全科医生治疗的患者职场冲突与心血管疾病之间的关联。在699家全科医生诊所（索引日期）中，确定了2005年至2014年期间有职场冲突经历初始记录的患者。我们仅纳入年龄在18岁至65岁之间、索引日期后随访时间至少180天且在记录职场欺凌之前未被诊断为心绞痛、心肌梗死、冠心病或中风的患者。总体而言，研究人群包括7374名经历冲突的患者和7374名作为对照用于分析的患者。主要结局指标是与职场冲突经历相关的心绞痛、心肌梗死和中风的发病率。经过最长五年的随访，经历职场冲突的个体中有2.9%受到心血管疾病影响，而对照组中只有1.4%受到影响（p值<0.001）。职场冲突与患心血管疾病风险增加1.63倍相关。最后,职场冲突对心肌梗死（OR=2.03）的影响高于心绞痛（OR=1.79）和中风（OR=1.56）。总体而言，我们发现职场冲突与心血管疾病之间存在显著关联。
