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尽管存在杀虫剂抗性,但疟疾媒介控制仍然重要。

Malaria Vector Control Still Matters despite Insecticide Resistance.

作者信息

Alout Haoues, Labbé Pierrick, Chandre Fabrice, Cohuet Anna

机构信息

Institut des Sciences de l'Evolution de Montpellier, CNRS, IRD, University of Montpellier, ISEM - UMR 5554, Montpellier, France.

Institut des Sciences de l'Evolution de Montpellier, CNRS, IRD, University of Montpellier, ISEM - UMR 5554, Montpellier, France.

出版信息

Trends Parasitol. 2017 Aug;33(8):610-618. doi: 10.1016/j.pt.2017.04.006. Epub 2017 May 9.

Abstract

Mosquito vectors' resistance to insecticides is usually considered a major threat to the recent progresses in malaria control. However, studies measuring the impact of interventions and insecticide resistance reveal inconsistencies when using entomological versus epidemiological indices. First, evaluation tests that do not reflect the susceptibility of mosquitoes when they are infectious may underestimate insecticide efficacy. Moreover, interactions between insecticide resistance and vectorial capacity reveal nonintuitive outcomes of interventions. Therefore, considering ecological interactions between vector, parasite, and environment highlights that the impact of insecticide resistance on the malaria burden is not straightforward and we suggest that vector control still matters despite insecticide resistance.

摘要

蚊虫媒介对杀虫剂的抗性通常被认为是疟疾控制近期进展面临的主要威胁。然而,在使用昆虫学指标与流行病学指标来衡量干预措施的影响和杀虫剂抗性时,研究结果并不一致。首先,那些在蚊虫具有传染性时无法反映其易感性的评估测试可能会低估杀虫剂的效果。此外,杀虫剂抗性与传病能力之间的相互作用揭示了干预措施出人意料的结果。因此,考虑媒介、寄生虫和环境之间的生态相互作用表明,杀虫剂抗性对疟疾负担的影响并非简单直接,并且我们认为,尽管存在杀虫剂抗性,病媒控制仍然至关重要。

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