Ranf Stefanie
Phytopathology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Str. 2, 85354 Freising-Weihenstephan, Germany.
Curr Opin Plant Biol. 2017 Aug;38:68-77. doi: 10.1016/j.pbi.2017.04.011. Epub 2017 May 10.
In plants, sensing of Pathogen/Microbe-Associated Molecular Patterns (PAMPs/MAMPs) and host-derived Damage-Associated Molecular Patterns (DAMPs) by host cell surface Pattern Recognition Receptors (PRRs) activates Pattern-Triggered Immunity (PTI). The identification of an increasing number of immunogenic patterns and PRRs illustrates that PTI is a universal defence mechanism against pathogens, pests, and parasitic plants, and that evolutionary selective pressure drives diversification of molecular patterns and diversity of PRRs. Further advances unravelled how some prototypical PRRs get activated to initiate metabolic adaptation and defence responses that stop invaders. Deeper insights into the repertoire of PRRs will reveal how plants manage to mount appropriate defence against diverse kinds of invaders and how we can biotechnologically exploit nature's design for sustainable agriculture.
在植物中，宿主细胞表面的模式识别受体（PRRs）对病原体/微生物相关分子模式（PAMPs/MAMPs）和宿主来源的损伤相关分子模式（DAMPs）的感知激活了模式触发免疫（PTI）。越来越多免疫原性模式和PRRs的鉴定表明，PTI是一种针对病原体、害虫和寄生植物的普遍防御机制，并且进化选择压力推动了分子模式的多样化和PRRs的多样性。进一步的进展揭示了一些典型的PRRs如何被激活以启动代谢适应和阻止入侵者的防御反应。对PRRs库的更深入了解将揭示植物如何设法对各种入侵者进行适当防御，以及我们如何通过生物技术利用自然设计实现可持续农业。
