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基于近亲数据的衰弱指数:来自墨西哥健康与老龄化研究的横断面分析。

A Frailty Index from Next-of-Kin Data: A Cross-Sectional Analysis from the Mexican Health and Aging Study.

作者信息

Pérez-Zepeda Mario Ulises, Cesari Matteo, Carrillo-Vega María Fernanda, Salinas-Escudero Guillermo, Tella-Vega Pamela, García-Peña Carmen

机构信息

Research Department, Instituto Nacional de Geriatría, Mexico City, Mexico.

Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

出版信息

Biomed Res Int. 2017;2017:6069374. doi: 10.1155/2017/6069374. Epub 2017 Apr 19.

Abstract

To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Aging Study (MHAS). Along with descriptive statistics, the frailty index (FI) was tested in regression models to assess its association with adverse outcomes previous to death: number of hospitalized days in the previous year and number of visits to a physician in the previous year, in unadjusted and adjusted models. From a total of 2,649 individuals the mean of age was 74.8 (±11.4) and 56.3% ( = 1,183) were women. The mean of the FI was of 0.279 (±SD 0.131, = 0.0-0.738) and distribution was biased to the right. There was a significant association ( < 0.001) between the FI and number of hospitalized days ( = 45.7, 95% CI 36.1-55.4, < 0.001) and for the number of visits to a physician ( = 25.93, 95% CI 19.27-32.6, < 0.001) both models adjusted for age and sex. The FI constructed with next-of-kin data showed similar characteristics to similar indexes of older adults. It was independently associated with health care use.

摘要

利用社区居住的50岁及以上成年人生命最后一年的近亲信息构建衰弱指数,并测试其与卫生服务利用情况的关联。对墨西哥健康与老龄化研究(MHAS)最后一波可获得的近亲数据进行横断面分析。除描述性统计外,还在回归模型中对衰弱指数(FI)进行了测试,以评估其与死亡前不良结局的关联:前一年的住院天数和前一年的就诊次数,分别在未调整和调整模型中进行分析。在总共两千六百四十九名个体中,平均年龄为74.8岁(±11.4),女性占56.3%(=1183人)。FI的平均值为0.279(±标准差0.131,范围=0.0 - 0.738),分布呈右偏态。FI与住院天数(=45.7,95%可信区间36.1 - 55.4,<0.001)以及就诊次数(=25.93,95%可信区间19.27 - 32.6,<0.001)之间存在显著关联,两个模型均对年龄和性别进行了调整。利用近亲数据构建的FI显示出与老年人类似指数相似的特征。它与医疗保健使用独立相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/5414507/fa9795a867cc/BMRI2017-6069374.001.jpg

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