正电子发射断层扫描分子成像引导下的活检：综述
PET Molecular Imaging-Directed Biopsy: A Review.
机构信息
1 Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1841 Clifton Rd NE, Atlanta, GA 30329.
2 Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA.
出版信息
AJR Am J Roentgenol. 2017 Aug;209(2):255-269. doi: 10.2214/AJR.17.18047. Epub 2017 May 15.
Abstract
OBJECTIVE
The purpose of this review is to summarize the applications of PET molecular imaging-directed biopsy of a variety of organs in the management of various diseases with a focus on cancers.
CONCLUSION
PET can yield metabolic information at the cellular and molecular levels, and PET-directed biopsy is playing an increasing role in the diagnosis and staging of diseases.
摘要
目的
本综述的目的是总结正电子发射断层扫描（PET）分子成像引导下对各种器官进行活检在多种疾病管理中的应用，重点是癌症。
结论
PET能够在细胞和分子水平上提供代谢信息，PET引导下的活检在疾病的诊断和分期中发挥着越来越重要的作用。
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3
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