Siregar Gontar, Sari Dina, Sungkar Taufik
University of Sumatera Utara, Gastroentero-Hepatology, Medan, Sumatera Utara 20122, Indonesia.
University of Sumatera Utara, Nutrition, Medan, Sumatera Utara, Indonesia.
Open Access Maced J Med Sci. 2017 Mar 19;5(2):137-141. doi: 10.3889/oamjms.2017.031. eCollection 2017 Apr 15.
and genes are associated with higher virulence. Vascular Endothelial Growth Factor (VEGF) is one important marker for neo-angiogenesis.
The purpose of this study was to investigate the relationship between VEGF serum levels with and genes in infection.
A cross-sectional study was done on eighty patients that consecutive admitted to endoscopy unit. The diagnosis of infection was based on rapid urease test. Serum samples were obtained to determine circulating VEGF level. Polymerase chain reaction was done to examine and genes. Data analysis were carried-out using SPSS version 22.
A total of 80 patients were examined. There were 45 (56.3%) patients infected with . There were 33 (73.3%) patients with positive. Serum VEGF levels in patients with the positive were significantly higher compared to the patients that have no . Serum levels of VEGF were significantly higher in positive than negative.
Serum VEGF level is correlated with infection and its virulence status. The more virulence of , gene, the higher serum VEGF levels were found.
和 基因与更高的毒力相关。血管内皮生长因子（VEGF）是新血管生成的一个重要标志物。
本研究的目的是调查VEGF血清水平与 感染中 和 基因之间的关系。
对连续入住内镜科的80例患者进行了横断面研究。 感染的诊断基于快速尿素酶试验。获取血清样本以测定循环VEGF水平。进行聚合酶链反应以检测 和 基因。使用SPSS 22版进行数据分析。
共检查了80例患者。有45例（56.3%）患者感染了 。有33例（73.3%）患者 呈阳性。 阳性患者的血清VEGF水平显著高于无 的患者。 阳性患者的血清VEGF水平显著高于阴性患者。
血清VEGF水平与 感染及其毒力状态相关。 基因的毒力越强，血清VEGF水平越高。
