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乳腺癌与运动:肥胖及免疫标志物的作用

Breast cancer and exercise: The role of adiposity and immune markers.

作者信息

Pudkasam Supa, Tangalakis Kathy, Chinlumprasert Nanthapan, Apostolopoulos Vasso, Stojanovska Lily

机构信息

Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, PO Box 14426, Melbourne VIC 8001 Australia; Faculty of Nursing Science, Assumption University, Bangkok, Thailand.

Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, PO Box 14426, Melbourne VIC 8001 Australia.

出版信息

Maturitas. 2017 Nov;105:16-22. doi: 10.1016/j.maturitas.2017.04.022. Epub 2017 May 8.

DOI:10.1016/j.maturitas.2017.04.022
PMID:28515012
Abstract

Currently, breast cancer accounts for a quarter of all cancers and 15% of cancer-specific deaths amongst females. The global occurrence of breast cancer has increased in the last decade whilst the mortality rate has decreased. Exercise can be beneficial to breast cancer patients through changes in adiposity and immune responses. Even though there is some evidence supporting the improvement of fat metabolism and immune function after an exercise program in breast cancer, randomized controlled studies are limited and require further comprehensive analysis in this population group. Herein, we identify the known effects of exercise programs on adiposity and immunological markers which can improve breast cancer outcomes.

摘要

目前,乳腺癌占所有癌症的四分之一,在女性癌症特异性死亡中占15%。在过去十年中,全球乳腺癌的发病率有所上升,而死亡率有所下降。运动可通过改变肥胖状况和免疫反应对乳腺癌患者有益。尽管有一些证据支持乳腺癌患者进行运动计划后脂肪代谢和免疫功能有所改善,但随机对照研究有限,且需要对该人群进行进一步的综合分析。在此,我们确定了运动计划对肥胖和免疫标志物的已知影响,这些影响可改善乳腺癌的预后。

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