Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Maternal and Child Healthcare Hospital of Yuhuatai District, Nanjing, China.
Sci Rep. 2017 May 17;7(1):2041. doi: 10.1038/s41598-017-02246-6.
This study evaluated the performance of plusoptiX A12C in detecting amblyopia risk factors (ARFs) in Chinese children aged 3-to-4-year. PlusoptiX examination was successfully conducted among 1,766 subjects without cycloplegia to detect refractive error, asymmetry and media opacity. Cycloplegic retinoscopy (CR) was conducted on 357 children suspected of having vision abnormalities. Statistical differences between CR and the device were confirmed using the mean spherical value (+1.41 ± 0.87 D versus +1.14 ± 0.81 D), cylindrical value (-0.47 ± 0.64 versus -0.84 ± 0.78) and spherical equivalent (SE) value (+1.17 ± 0.84 D versus +0.72 ± 0.64 D) (all P < 0.0001). In the emmetropia group, the differences were statistically significant for the cylinder and SE (all P < 0.0001) but not the sphere (P = 0.33). In the hyperopia group, the differences were statistically significant for the sphere, cylinder and SE (all P < 0.0001). For refractive and strabismic ARFs detection, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated, respectively.
本研究评估了 plusoptiX A12C 在检测中国 3 至 4 岁儿童弱视风险因素（ARFs）方面的性能。对 1766 名未进行睫状肌麻痹的受试者进行了 plusoptiX 检查，以检测屈光不正、不对称和介质混浊。对 357 名疑似视力异常的儿童进行了睫状肌麻痹检影验光（CR）。使用平均球镜值（+1.41±0.87 D 与 +1.14±0.81 D）、柱镜值（-0.47±0.64 与 -0.84±0.78）和等效球镜值（+1.17±0.84 D 与 +0.72±0.64 D）确认了 CR 和设备之间的统计学差异（均 P<0.0001）。在正视组中，柱镜和 SE 的差异具有统计学意义（均 P<0.0001），但球镜无差异（P=0.33）。在远视组中，球镜、柱镜和 SE 的差异具有统计学意义（均 P<0.0001）。对于屈光和斜视 ARFs 检测，分别计算了敏感性、特异性、阳性预测值和阴性预测值。
