NextProt 肽独特性检查器：蛋白质组学社区的工具。
The neXtProt peptide uniqueness checker: a tool for the proteomics community.
机构信息
Department of Human Protein Science, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
CALIPHO Group, SIB Swiss Institute of Bioinformatics, CMU, 1211 Geneva 4, Switzerland.
出版信息
Bioinformatics. 2017 Nov 1;33(21):3471-3472. doi: 10.1093/bioinformatics/btx318.
SUMMARY
The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid variants.
AVAILABILITY AND IMPLEMENTATION
The pepx program is available at https://github.com/calipho-sib/pepx and can be launched from the command line or through a cgi web interface. Indexing requires a sequence file in FASTA format. The peptide uniqueness checker tool is freely available on the web at https://www.nextprot.org/tools/peptide-uniqueness-checker and from the neXtProt API at https://api.nextprot.org/.
CONTACT
摘要
neXtProt 的肽独特性检查器允许科学家定义哪些肽可用于验证人类蛋白质的存在，即考虑到等电异位取代、选择性剪接和单个氨基酸变异，肽可唯一或多次映射到人类蛋白质序列。
可用性和实施
pepx 程序可在 https://github.com/calipho-sib/pepx 上获得，并可从命令行或通过 cgi web 界面启动。索引需要 FASTA 格式的序列文件。肽独特性检查器工具可在 https://www.nextprot.org/tools/peptide-uniqueness-checker 上免费在线使用，并可从 neXtProt API 在 https://api.nextprot.org/ 获得。
联系信息
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