Pergola Brianna L, Moonie Sheniz, Pharr Jennifer, Bungum Timothy, Anderson Julia L
School of Community Health Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
School of Community Health Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United States.
Sleep Med. 2017 Jun;34:209-216. doi: 10.1016/j.sleep.2017.03.006. Epub 2017 Mar 29.
Associations between sleep duration and cardiovascular conditions have been inconsistent. Both short and long sleep duration are associated with increased risk for diabetes, hypertension, obesity, high cholesterol, depression, and overall metabolic dysfunction; all of which are cardiovascular disease risk factors. This study aimed to determine if deficient or excessive sleep duration is associated with cardiovascular conditions.
Data were obtained from the 2013 Behavioral Risk Factor Surveillance System for the state of Nevada. A total of 5101 participants completed the survey and answered questions as to whether they had ever had a cardiovascular condition ie, myocardial infarction, coronary heart disease or angina, and stroke. Multiple logistic regression was implemented during analyses and yielded four models including demographics, co-morbidity, behavior, and final significant variables.
Six significant predictor variables were identified in the final model. Sleep duration was statistically significant (p < 0.0001). Individuals having deficient sleep, eg, 1-4 h a night, were 2.4 times more likely to have a cardiovascular condition versus those sleeping 7-9 h per night (OR = 2.412, CI = 1.139, 5.107). As for individuals who sleep excessively, eg, 10-18 h a night, they were nearly 7.2 times more likely to have a cardiovascular condition, compared to individuals who receive a normal night's sleep (OR = 7.170, CI = 3.284, 15.654).
Both deficient and excessive sleep duration were significantly associated with a cardiovascular condition, even after adjustment for covariates. The findings from this study can be used as additional evidence to encourage further research on improving sleep by developing future treatment therapies, and recommendations, that may help lower the risk of cardiovascular disease conditions.
睡眠时间与心血管疾病之间的关联并不一致。睡眠时间过短和过长均与糖尿病、高血压、肥胖、高胆固醇、抑郁症及整体代谢功能障碍风险增加有关;而所有这些都是心血管疾病的危险因素。本研究旨在确定睡眠时间不足或过长是否与心血管疾病有关。
数据来自内华达州2013年行为危险因素监测系统。共有5101名参与者完成了调查,并回答了他们是否曾患心血管疾病,即心肌梗死、冠心病或心绞痛以及中风。分析过程中采用了多元逻辑回归,并得出四个模型,包括人口统计学、合并症、行为及最终的显著变量。
最终模型中确定了六个显著预测变量。睡眠时间具有统计学意义(p < 0.0001)。睡眠不足的个体,如每晚睡眠1 - 4小时,患心血管疾病的可能性是每晚睡7 - 9小时者的2.4倍(OR = 2.412,CI = 1.139,5.107)。至于睡眠过多的个体,如每晚睡10 - 18小时,与正常睡眠者相比,患心血管疾病的可能性几乎高7.2倍(OR = 7.170,CI = 3.284,15.6�4)。
即使在对协变量进行调整后,睡眠时间不足和过长均与心血管疾病显著相关。本研究结果可作为额外证据,鼓励通过开发未来的治疗方法和建议来进一步研究改善睡眠,这可能有助于降低心血管疾病的风险。