Buckingham Lindsey, Becher Julie, Voytek Chelsea D, Fiore Danielle, Dunbar Debora, Davis-Vogel Annet, Metzger David S, Frank Ian
HIV Prevention Research Division, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
HIV Prevention Research Division, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Vaccine. 2017 Jun 14;35(27):3498-3505. doi: 10.1016/j.vaccine.2017.05.002. Epub 2017 May 16.
To compare the use of four different social media sites to recruit men who have sex with men (MSM) and transgender women to a phase 2b HIV prevention vaccine trial, HVTN 505.
Retrospective, observational study.
The University of Pennsylvania HIV Vaccine Trials Unit (Penn HVTU) employed street outreach and online recruitment methods to recruit participants for HVTN 505 using a combination of national recruitment images/messages with Philadelphia-specific language and imagery. We compared the efficiency (number of enrolled participants per number of completed phone screens) and effectiveness (number of enrolled participants per time interval employed) of each strategy, as well as the demographics and risk behaviors of the populations.
Online recruitment strategies populated 37% (71/191) of trial participants at our site. Among the four social media strategies employed, 45.1% (32/71) were enrolled through Facebook, 16.9% (12/71) through Craigslist, 15.5% (11/71) through a web-based marketing company (WBMC), and 22.5% (16/71) via GRINDR. The number of participants enrolled per month of strategy and the months the strategy was employed were Facebook - 32(33months), Craigslist - 12(33months), WBMC - 11(6months), and GRINDR - 16(0.56months). In-person and online recruitment strategies yielded participants of similar demographics and levels of risk behavior.
Use of several social media recruitment modalities produced large numbers of MSM engaging in high risk behavior and willing to participate in an HIV prevention vaccine trial. In comparison to other social media and online strategies, recruitment via GRINDR was the most effective.
比较使用四个不同社交媒体平台招募男男性行为者（MSM）和跨性别女性参与2b期HIV预防疫苗试验HVTN 505的情况。
回顾性观察研究。
宾夕法尼亚大学HIV疫苗试验单位（Penn HVTU）采用街头宣传和在线招募方法，结合全国性招募图片/信息与费城特色语言和图像，为HVTN 505招募参与者。我们比较了每种策略的效率（每完成的电话筛选人数中登记参与者的数量）和效果（每个时间间隔内登记参与者的数量），以及人群的人口统计学特征和风险行为。
在线招募策略为我们研究点的37%（71/191）的试验参与者提供了来源。在所采用的四种社交媒体策略中，45.1%（32/71）通过Facebook招募，16.9%（12/71）通过Craigslist招募，15.5%（11/71）通过一家网络营销公司（WBMC）招募，22.5%（16/71）通过GRINDR招募。每种策略每月招募的参与者数量以及该策略使用的月数分别为：Facebook - 32人（33个月），Craigslist - 12人（33个月），WBMC - 11人（6个月），GRINDR - 16人（0.56个月）。面对面和在线招募策略产生的参与者在人口统计学特征和风险行为水平方面相似。
使用多种社交媒体招募方式吸引了大量从事高风险行为且愿意参与HIV预防疫苗试验的男男性行为者。与其他社交媒体和在线策略相比，通过GRINDR进行招募最为有效。
