Daniel Oved, Mauskop Alexander
Headache & Facial Pain Clinic, Laniado Medical Center, 16 Divrei Chaim, Netanya, 4244916, ISRAEL.
Clinical Neurology, SUNY Downstate Medical Center, Brooklyn, NY, 11203, USA.
Curr Treat Options Neurol. 2016 Apr;18(4):14. doi: 10.1007/s11940-016-0398-1.
People who suffer from headaches often prefer nutraceutical treatment over traditional pharmacological approaches, due to fear of possible side effects, drug dependence, or addiction. Since treatment with nutraceuticals does not require a doctor's prescription, many patients rely on their own judgment as to when and which one to take, often without consultation or guidance from their physician. Some physicians could provide information about potential efficacy and side effects of various products, but many are not familiar with the nutraceuticals. Widespread skepticism persists among doctors about the effectiveness of these treatments. This is largely due to the lack of rigorous clinical studies. However, even when incontrovertible scientific evidence exists, many physicians remain distrustful of the evidence. The following review summarizes randomized controlled trials of some of the most commonly used non-pharmacological treatments, including magnesium, coenzyme Q10, riboflavin (vitamin B2), petasites, and feverfew (Table 1).
由于担心可能出现的副作用、药物依赖或成瘾问题，患有头痛的人通常更喜欢采用营养保健品治疗而非传统的药理学方法。由于使用营养保健品进行治疗不需要医生处方，许多患者自行判断何时服用以及服用哪种产品，往往在没有咨询医生或医生指导的情况下进行。一些医生可以提供有关各种产品潜在疗效和副作用的信息，但许多医生并不熟悉营养保健品。医生们对这些治疗方法的有效性普遍持怀疑态度。这在很大程度上是由于缺乏严格的临床研究。然而，即使存在无可争议的科学证据，许多医生仍然不信任这些证据。以下综述总结了一些最常用的非药物治疗方法的随机对照试验，包括镁、辅酶Q10、核黄素（维生素B2）、蜂斗菜和小白菊（表1）。
