Hanada N, Kido S, Terashima M, Nishikawa K, Morishima T
Department of Paediatrics, Nagoya University School of Medicine, Japan.
Arch Dis Child. 1988 Dec;63(12):1470-3. doi: 10.1136/adc.63.12.1470.
For the early diagnosis of herpes simplex encephalitis IgG and IgM antibodies to herpes simplex virus in cerebrospinal fluid were measured by an enzyme linked immunosorbent assay (ELISA) and a local production index was calculated. Using these three criteria, 31 cases of various neurological illnesses were analysed. All eight cases of herpes simplex encephalitis were diagnosed correctly in the acute phase, and there were no false positive results.
为早期诊断单纯疱疹性脑炎,采用酶联免疫吸附测定(ELISA)法检测脑脊液中单纯疱疹病毒的IgG和IgM抗体,并计算局部产生指数。运用这三项标准,对31例各种神经系统疾病病例进行了分析。8例单纯疱疹性脑炎在急性期均被正确诊断,且无假阳性结果。