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基因表达谱分析在……中

gene expression profiling in .

作者信息

Massimino Luca

机构信息

Molecular Oncology Unit, San Gerardo Hospital, Monza, Italy.

出版信息

F1000Res. 2017 Jan 23;6:69. doi: 10.12688/f1000research.10631.1. eCollection 2017.

Abstract

The cannabis plant and its active ingredients (i.e., cannabinoids and terpenoids) have been socially stigmatized for half a century. Luckily, with more than 430,000 published scientific papers and about 600 ongoing and completed clinical trials, nowadays cannabis is employed for the treatment of many different medical conditions. Nevertheless, even if a large amount of high-throughput functional genomic data exists, most researchers feature a strong background in molecular biology but lack advanced bioinformatics skills. In this work, publicly available gene expression datasets have been analyzed giving rise to a total of 40,224 gene expression profiles taken from cannabis plant tissue at different developmental stages. The resource presented here will provide researchers with a starting point for future investigations with .

摘要

大麻植物及其活性成分(即大麻素和萜类化合物)在社会上遭受污名化已有半个世纪之久。幸运的是,如今已有超过43万篇已发表的科学论文以及约600项正在进行和已完成的临床试验,大麻被用于治疗多种不同的医疗病症。然而,即便存在大量高通量功能基因组数据,但大多数研究人员具备强大的分子生物学背景,却缺乏先进的生物信息学技能。在这项工作中,对公开可用的基因表达数据集进行了分析,共产生了40224个取自大麻植物不同发育阶段组织的基因表达谱。此处展示的资源将为研究人员开展未来的研究提供一个起点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fef/5414814/3df35a6aabb3/f1000research-6-11455-g0000.jpg

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