Mukherjee Anirban, Bal Chandrasekhar, Tripathi Madhavi, Das Chandan Jyoti, Shamim Shamim Ahmed
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Indian J Nucl Med. 2017 Apr-Jun;32(2):148-149. doi: 10.4103/0972-3919.202254.
20 year old post renal transplant patient developed recurrent episodes of seizure. MRI revealed focal lesion in right parieto-occipital lobe with perilesional edema. FDG PET-CT revealed multiple hypermetabolic lesions in bilateral cerebral hemisphere. Subsequent biopsy from the lesion demonstrated bradyzoites of Toxoplasma gondii with inflammatory cells and thereby, a confirmatory diagnosis of cerebral toxoplasmosis was made. This case demonstrates the fact that increased FDG uptake in cerebral lesions in post transplant patient should be interpreted with caution and confirmed with histopathological correlation.
一名20岁的肾移植术后患者出现反复发作的癫痫。磁共振成像（MRI）显示右侧顶枕叶有局灶性病变并伴有病变周围水肿。氟代脱氧葡萄糖正电子发射断层扫描（FDG PET-CT）显示双侧大脑半球有多个高代谢病变。随后对病变进行活检，发现有伴有炎症细胞的弓形虫缓殖子，从而确诊为脑弓形虫病。该病例表明，对于移植后患者脑病变中FDG摄取增加的情况，应谨慎解读，并通过组织病理学相关性予以证实。
