Waters Flavie, Moretto Umberto, Dang-Vu Thien Thanh
School of Psychological Science, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia.
Clinical Research Centre, Graylands Hospital, North Metropolitan Health Service-Mental Health, Perth, Western Australia, Australia.
Curr Psychiatry Rep. 2017 Jul;19(7):37. doi: 10.1007/s11920-017-0789-3.
Little is known about the presence of parasomnias such as nightmare disorder, sleep paralysis, REM sleep behavior disorder (RBD), and sleep-related eating disorders (SRED) in people with mental illness. A predominant view suggests that psychotropic medications might be contributing to parasomnias. This article summarizes knowledge regarding the relationships between psychiatric disorders and parasomnias, and possible confounds. A systematic search of the literature in the past 10 years identified 19 articles.
There were significantly elevated rates of parasomnias in psychiatric disorders (average prevalence of nightmares was 38.9%, sleep paralysis 22.3%, SRED 9.9%, sleepwalking 8.5%, and RBD 3.8%). Medication usage was only one of many risk factors (other sleep disorders, medical comorbidities, and substance abuse) which were associated with parasomnias. A strong association exists between mental illness and parasomnias which is not fully explained by medications. Prospective longitudinal studies are needed to develop a better understanding of the unique and shared variance from multiple risk factors.
关于精神疾病患者中诸如噩梦障碍、睡眠瘫痪、快速眼动睡眠行为障碍(RBD)以及睡眠相关进食障碍(SRED)等异态睡眠的存在情况,人们了解甚少。一种主流观点认为精神药物可能导致异态睡眠。本文总结了有关精神疾病与异态睡眠之间关系以及可能的混杂因素的知识。对过去10年的文献进行系统检索后确定了19篇文章。
精神疾病患者中异态睡眠的发生率显著升高(噩梦的平均患病率为38.9%,睡眠瘫痪为22.3%,SRED为9.9%,梦游为8.5%,RBD为3.8%)。药物使用只是与异态睡眠相关的众多风险因素之一(其他睡眠障碍、内科合并症和物质滥用)。精神疾病与异态睡眠之间存在强烈关联,而药物并不能完全解释这种关联。需要进行前瞻性纵向研究,以更好地理解多种风险因素的独特和共同差异。