钯催化通过电化学氧化的 C(sp)-H 乙酰氧基化。
Palladium-Catalyzed C(sp)-H Acetoxylation via Electrochemical Oxidation.
机构信息
Institute of Pharmaceutical Science, China Pharmaceutical University , Nanjing, P. R. China.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, P. R. China.
出版信息
Org Lett. 2017 Jun 2;19(11):2905-2908. doi: 10.1021/acs.orglett.7b01138. Epub 2017 May 24.
Palladium-catalyzed arene C(sp)-H acetoxylation has emerged as a powerful tool to construct a carbon-oxygen (C-O) bond. However, the requirement of stoichiometric chemical oxidants for this transformation possesses a significant disadvantage. To solve this fundamental problem, we now report an anodic oxidation strategy to achieve arene C(sp)-H acetoxylation.
钯催化芳环 C(sp 2 )-H 乙酰氧基化已成为构建碳-氧 (C-O) 键的有力工具。然而，这种转化需要化学计量的氧化剂，这是一个显著的缺点。为了解决这个基本问题，我们现在报告了一种阳极氧化策略，以实现芳环 C(sp 2 )-H 乙酰氧基化。
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