Amdjadi Parisa, Nojehdehian Hanieh, Najafi Farhood, Ghasemi Amir, Seifi Massoud, Dashtimoghadam Erfan, Fahimipour Farahnaz, Tayebi Lobat
1 School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Marquette University School of Dentistry, Milwaukee, WI, USA.
J Biomater Appl. 2017 Jul;32(1):3-11. doi: 10.1177/0885328217709609. Epub 2017 May 24.
Since octafluoropentyl methacrylate is an antifouling polymer, surface modification of polyether ether ketone with octafluoropentyl methacrylate is a practical approach to obtaining anti-biofilm biocompatible devices. In the current study, the surface treatment of polyether ether ketone by the use of ultraviolet irradiation, so as to graft (octafluoropentyl methacrylate) polymer chains, was initially implemented and then investigated. The Fourier-transform infrared and nuclear magnetic resonance spectra corroborated the appearance of new signals associated with the fluoroacrylate group. Thermogravimetric curves indicated enhanced asymmetry in the polymer structure due to the introduction of the said new groups. Measuring the peak area in differential scanning calorimetry experiments also showed additional bond formation. Static water contact angle measurements indicated a change in wettability to the more hydrophobic surface. The polyether ether ketone-octafluoropentyl methacrylate surface greatly reduced the protein adsorption. This efficient method can modulate and tune the surface properties of polyether ether ketone according to specific applications.
由于甲基丙烯酸八氟戊酯是一种防污聚合物，用甲基丙烯酸八氟戊酯对聚醚醚酮进行表面改性是获得抗生物膜生物相容性装置的一种实用方法。在当前研究中，首先实施了利用紫外线辐射对聚醚醚酮进行表面处理，以便接枝（甲基丙烯酸八氟戊酯）聚合物链，然后进行了研究。傅里叶变换红外光谱和核磁共振光谱证实了与氟丙烯酸酯基团相关的新信号的出现。热重曲线表明由于引入了所述新基团，聚合物结构中的不对称性增强。在差示扫描量热法实验中测量峰面积也显示有额外的键形成。静态水接触角测量表明润湿性向更疏水的表面发生了变化。聚醚醚酮 - 甲基丙烯酸八氟戊酯表面大大降低了蛋白质吸附。这种有效方法可以根据特定应用来调节和调整聚醚醚酮的表面性质。
