Summanen P, Tönjum A M
King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
Acta Ophthalmol Suppl (1985). 1988;184:107-11. doi: 10.1111/j.1755-3768.1988.tb02639.x.
The prevalence of exfoliation syndrome among Saudis was determined during the National Survey of Blindness and Eye Disease in 1984 in Kingdom of Saudi Arabia. The subsample of this study consists of 376 persons aged 40 years or more from 50 different locations examined under mydriasis by the authors using Kowa hand-held microscope. There were 192 men and 184 women with the mean age of 56.0 +/- 1.2 years (median 53.5 years, range 40-95 years). The overall prevalence of exfoliation syndrome was 9.3%: in the age group 40 to 49 years 1.6%, 50 to 59 years 7.8%, 60 to 69 years 8.9%, and 26.5% in persons 70 years of age and over. No significant association was found between exfoliation syndrome and sex or parental kinship. In 16 persons the exfoliation syndrome was unilateral, and in 19 persons bilateral. In 24 eyes the phenomenon could not be evaluated due to the anterior segment pathology. Exfoliation syndrome was associated with higher intraocular pressure (20 +/- 3 mmHg (n = 49) vs. 17 +/- 0.4 mmHg (n = 601), P less than 0.05), and more cataract changes (P less than 0.001) than eyes without. These eyes were also associated with poorer visual acuity than the eyes without exfoliation syndrome: in 26 of 35 persons with exfoliation syndrome, the affected eye was the better eye but in 35% the vision was less than 0.05 (less than 3/60) i.e. the person was blind, compared to 6% of persons whose better eye did not have exfoliation syndrome (P less than 0.001).
1984年沙特阿拉伯王国全国盲症和眼病调查期间，确定了沙特人中剥脱综合征的患病率。本研究的子样本包括来自50个不同地点的376名40岁及以上的人，作者使用柯瓦手持显微镜在散瞳状态下对其进行了检查。其中有192名男性和184名女性，平均年龄为56.0±1.2岁（中位数53.5岁，范围40 - 95岁）。剥脱综合征的总体患病率为9.3%：40至49岁年龄组为1.6%，50至59岁年龄组为7.8%，60至69岁年龄组为8.9%，70岁及以上人群为26.5%。未发现剥脱综合征与性别或亲子关系之间存在显著关联。16人的剥脱综合征为单侧，19人为双侧。24只眼睛由于前段病变无法评估该现象。与没有剥脱综合征的眼睛相比，剥脱综合征与较高的眼压相关（20±3 mmHg（n = 49）对17±0.4 mmHg（n = 601），P<0.05），并且白内障变化更多（P<0.001）。这些眼睛的视力也比没有剥脱综合征的眼睛差：在35名患有剥脱综合征的人中，26人的患眼是较好的眼睛，但35%的人的视力低于0.05（低于3/60），即此人失明，而较好的眼睛没有剥脱综合征的人中这一比例为6%（P<0.001）。
