Cashwell L F, Shields M B
Department of Ophthalmology, Wake Forest University Medical Center, Winston-Salem, North Carolina.
Acta Ophthalmol Suppl (1985). 1988;184:99-102. doi: 10.1111/j.1755-3768.1988.tb02637.x.
A prospective study of 2,121 patients, 30 years of age or older, examined in two clinics in the southeastern United States with dilated slit-lamp biomicroscopy, revealed the exfoliation syndrome in 1.6% of the total population and in 6.0% of an open-angle glaucoma subpopulation. All but one of the 33 patients with exfoliation syndrome were over age 60 years, and the prevalence of exfoliation syndrome in the subgroup over age 60 was 3.2%. Among the patients over age 60 who did not have open-angle glaucoma, 1.6% had exfoliation syndrome. By chi square analysis, the prevalence of the exfoliation syndrome in the over age 60 population without glaucoma was found to be significantly less (P = 0.00009) than reported in studies from other geographic areas.
一项对2121名30岁及以上患者的前瞻性研究在美国东南部的两家诊所进行，采用散瞳裂隙灯生物显微镜检查。结果显示，在总人口中，剥脱综合征的患病率为1.6%，在开角型青光眼亚组中为6.0%。33例剥脱综合征患者中，除1例以外，其余均超过60岁，60岁以上亚组中剥脱综合征的患病率为3.2%。在60岁以上且没有开角型青光眼的患者中，1.6%患有剥脱综合征。通过卡方分析发现，60岁以上无青光眼人群中剥脱综合征的患病率显著低于其他地理区域的研究报告（P = 0.00009）。
