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传染病的即时检测:过去、现在与未来

Point-of-Care Testing for Infectious Diseases: Past, Present, and Future.

作者信息

Kozel Thomas R, Burnham-Marusich Amanda R

机构信息

Department of Microbiology & Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada, USA; DxDiscovery, Inc., Reno, Nevada, USA

Department of Microbiology & Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada, USA; DxDiscovery, Inc., Reno, Nevada, USA.

出版信息

J Clin Microbiol. 2017 Aug;55(8):2313-2320. doi: 10.1128/JCM.00476-17. Epub 2017 May 24.

DOI:10.1128/JCM.00476-17
PMID:28539345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5527409/
Abstract

Point-of-care (POC) diagnostics provide rapid actionable information for patient care at the time and site of an encounter with the health care system. The usual platform has been the lateral flow immunoassay. Recently, emerging molecular diagnostics have met requirements for speed, low cost, and ease of use for POC applications. A major driver for POC development is the ability to diagnose infectious diseases at sites with a limited infrastructure. The potential use in both wealthy and resource-limited settings has fueled an intense effort to build on existing technologies and to generate new technologies for the diagnosis of a broad spectrum of infectious diseases.

摘要

即时检验(POC)诊断能够在患者与医疗保健系统接触的当时当地,为患者护理提供快速且可采取行动的信息。常用平台一直是侧向流动免疫测定法。最近,新兴的分子诊断技术已满足即时检验应用对速度、低成本和易用性的要求。即时检验发展的一个主要驱动力是能够在基础设施有限的地点诊断传染病。在富裕和资源有限的环境中的潜在用途推动了人们大力在现有技术基础上进行改进,并开发用于诊断多种传染病的新技术。

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