Yasutake Kenichiro, Moriguchi Ririko, Kajiyama Tomomi, Miyazaki Hitomi, Abe Shimako, Masuda Takashi, Imai Katsumi, Iwamoto Masako, Tsuda Hiroko, Obe Masayo, Kawate Hisaya, Ueno Hiromi, Ono Misaki, Goromaru Ryoko, Ohe Kenji, Enjoji Munechika, Tsuchihashi Takuya, Nakano Shuji
Health Promotion Center, Nakamura Gakuen University, Fukuoka, Japan.
Health Care Center, Fukuoka University, Fukuoka, Japan.
J Clin Hypertens (Greenwich). 2017 Jul;19(7):653-660. doi: 10.1111/jch.13025. Epub 2017 May 23.
The authors investigated interannual differences in the sodium excretion levels of young healthy Japanese women as estimated from spot urine analysis at Nakamura Gakuen University from 1995 to 2015. Participants included 4931 women aged 18 to 20 years who were classified into three time periods according to year of health check: first (1995-2001), second (2002-2007), and third (2008-2015). Estimated daily urinary sodium and potassium excretion levels and the sodium to potassium ratio were 120.6±31.9 mmol, 35.2±8.1 mmol, and 3.5±0.9, respectively. Adjusted for body weight, sodium excretion, and potassium excretion significantly decreased in the second and third period compared with the first period (P<.001). Systolic blood pressure also decreased in the same way between time periods (P<.001). Estimated urinary excretion levels of sodium and potassium in young Japanese women have decreased over the past 20 years independently of body weight.
作者通过对中村学园大学1995年至2015年期间年轻健康日本女性的随机尿样分析，研究了钠排泄水平的年际差异。参与者包括4931名年龄在18至20岁之间的女性，她们根据健康检查年份分为三个时间段：第一个时间段（1995 - 2001年）、第二个时间段（2002 - 2007年）和第三个时间段（2008 - 2015年）。估计的每日尿钠和钾排泄水平以及钠钾比分别为120.6±31.9 mmol、35.2±8.1 mmol和3.5±0.9。与第一个时间段相比，在调整体重后，第二个和第三个时间段的钠排泄和钾排泄显著降低（P<0.001）。收缩压在不同时间段也以相同方式降低（P<0.001）。在过去20年中，日本年轻女性的尿钠和钾排泄水平估计值下降，且与体重无关。
