• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

两种富含小淋巴细胞的肿瘤,B1B2型胸腺瘤和小淋巴细胞淋巴瘤,混合于一个肿瘤块中。病例报告。

Two neoplasms rich in small lymphocytes, B1B2 thymoma and small lymphocytic lymphoma, intermingled in one tumor mass. A case report.

作者信息

Szolkowska Malgorzata, Langfort Renata, Winiarski Sebastian, Zaremba Jacek, Prochorec-Sobieszek Monika, Rymkiewicz Grzegorz, Jaskiewicz Piotr, Kowalski Dariusz M

出版信息

Pol J Pathol. 2017;68(1):75-81. doi: 10.5114/pjp.2017.67620.

DOI:10.5114/pjp.2017.67620
PMID:28547984
Abstract

We present a case of a 52-year-old man with myasthenia gravis and a mediastinal tumor who was admitted to our hospital for surgical treatment. The pathologic examination of the resected tumor revealed a very rare case of a collision tumor: a B1B2 thymoma and a small lymphocytic lymphoma. Flow cytometry of the peripheral blood revealed the presence of a small number of leukemic cells. After postoperative irradiation of the mediastinum and chemotherapy a complete response in both diseases was achieved. The case confirms that a pathologist should always be aware that two different neoplasms can coexist in rare cases.

摘要

我们报告一例52岁患有重症肌无力和纵隔肿瘤的男性患者,他因手术治疗入院。切除肿瘤的病理检查显示为一种非常罕见的碰撞瘤:B1B2型胸腺瘤和小淋巴细胞淋巴瘤。外周血流式细胞术显示存在少量白血病细胞。纵隔术后放疗和化疗后,两种疾病均实现完全缓解。该病例证实病理学家应始终意识到在罕见情况下两种不同的肿瘤可能共存。

相似文献

1
Two neoplasms rich in small lymphocytes, B1B2 thymoma and small lymphocytic lymphoma, intermingled in one tumor mass. A case report.两种富含小淋巴细胞的肿瘤,B1B2型胸腺瘤和小淋巴细胞淋巴瘤,混合于一个肿瘤块中。病例报告。
Pol J Pathol. 2017;68(1):75-81. doi: 10.5114/pjp.2017.67620.
2
Concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma in an anterior mediastinal mass.前纵隔肿物合并胸腺瘤、胸腺癌及T淋巴母细胞白血病/淋巴瘤。
Pathol Res Pract. 2015 Sep;211(9):693-6. doi: 10.1016/j.prp.2015.06.002. Epub 2015 Jun 9.
3
Composite thymoma and chronic lymphocytic leukemia/small lymphocytic lymphoma involving the anterior mediastinum.
Arch Pathol Lab Med. 2003 Feb;127(2):E76-9. doi: 10.5858/2003-127-e76-CTACLL.
4
Sarcomatoid thymic carcinoma arising in metaplastic thymoma: a case report.起源于化生型胸腺瘤的肉瘤样胸腺癌:一例报告
Int J Surg Pathol. 2011 Oct;19(5):677-80. doi: 10.1177/1066896909355458. Epub 2009 Dec 24.
5
A case report of sclerosing thymoma of the anterior mediastinum: an exceedingly rare morphology.前纵隔硬化性胸腺瘤病例报告:一种极为罕见的形态学表现。
Int J Clin Exp Pathol. 2015 Apr 1;8(4):4233-7. eCollection 2015.
6
Multiple thymoma with myasthenia gravis: report of a case.合并重症肌无力的多发性胸腺瘤:1例报告
Surg Today. 2003;33(1):49-51. doi: 10.1007/s005950300008.
7
Thymic carcinoid tumor combined with thymoma--neuroendocrine differentiation in thymoma?胸腺类癌合并胸腺瘤——胸腺瘤中的神经内分泌分化?
J Korean Med Sci. 1993 Dec;8(6):458-63. doi: 10.3346/jkms.1993.8.6.458.
8
Metaplastic thymoma with myasthenia gravis presumably caused by an accumulation of intratumoral immature T cells: a case report.伴重症肌无力的化生性胸腺瘤可能由肿瘤内不成熟T细胞积聚所致:一例报告
Int J Clin Exp Pathol. 2015 Nov 1;8(11):15375-80. eCollection 2015.
9
Thymoma in a dog with a part of granular cell proliferation and concurrent lymphoma cells.
J Vet Med Sci. 2004 Jun;66(6):713-5. doi: 10.1292/jvms.66.713.
10
Collision tumor of primary merkel cell carcinoma and chronic lymphocytic leukemia/small lymphocytic lymphoma, diagnosed on ultrasound-guided fine-needle aspiration biopsy: a unique case report and review of literature.经超声引导下细针穿刺活检诊断的原发性默克尔细胞癌与慢性淋巴细胞白血病/小淋巴细胞淋巴瘤碰撞瘤:一例独特病例报告及文献复习
Diagn Cytopathol. 2015 Jan;43(1):66-71. doi: 10.1002/dc.23127. Epub 2014 Mar 8.

引用本文的文献

1
Identifying small thymomas from other asymptomatic anterior mediastinal nodules based on CT images using logistic regression.使用逻辑回归基于CT图像从其他无症状的前纵隔结节中识别小胸腺瘤。
Front Oncol. 2025 Jul 21;15:1590710. doi: 10.3389/fonc.2025.1590710. eCollection 2025.
2
Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report.AB型胸腺瘤合并腺癌的前纵隔碰撞瘤:1例报告
Front Oncol. 2025 May 16;15:1495627. doi: 10.3389/fonc.2025.1495627. eCollection 2025.
3
Concurrent myasthenia gravis-related cervical thymoma in a patient with diffuse large B-cell lymphoma: a case report.
患者弥漫性大 B 细胞淋巴瘤合并伴发重症肌无力相关的颈胸腺肿瘤:病例报告。
J Med Case Rep. 2022 Jan 12;16(1):10. doi: 10.1186/s13256-021-03225-2.
4
Thymoma appearing 9 years after the resection of squamous cell carcinoma of the lip: A case report of triple primary tumors and literature review.唇部鳞状细胞癌切除术后9年出现胸腺瘤:一例三原发性肿瘤病例报告及文献复习
Oncol Lett. 2019 Sep;18(3):2777-2788. doi: 10.3892/ol.2019.10675. Epub 2019 Jul 26.
5
Primary mediastinal neoplasms: a report of 1,005 cases from a single institution.原发性纵隔肿瘤:来自单一机构的1005例报告。
J Thorac Dis. 2019 Jun;11(6):2498-2511. doi: 10.21037/jtd.2019.05.42.
6
Value of CT spectral imaging in the differential diagnosis of thymoma and mediastinal lymphoma.CT光谱成像在胸腺瘤与纵隔淋巴瘤鉴别诊断中的价值
Br J Radiol. 2019 Mar;92(1095):20180598. doi: 10.1259/bjr.20180598. Epub 2018 Dec 3.
7
Complete resection of an anterior mediastinal tumor by total arch replacement and pulmonary artery trunk plasty with a pericardial patch: A case report.经全弓置换及带心包补片的肺动脉干成形术完整切除前纵隔肿瘤:1例报告
Ann Med Surg (Lond). 2018 Sep 25;35:82-85. doi: 10.1016/j.amsu.2018.09.023. eCollection 2018 Nov.