Szolkowska Malgorzata, Langfort Renata, Winiarski Sebastian, Zaremba Jacek, Prochorec-Sobieszek Monika, Rymkiewicz Grzegorz, Jaskiewicz Piotr, Kowalski Dariusz M
Pol J Pathol. 2017;68(1):75-81. doi: 10.5114/pjp.2017.67620.
We present a case of a 52-year-old man with myasthenia gravis and a mediastinal tumor who was admitted to our hospital for surgical treatment. The pathologic examination of the resected tumor revealed a very rare case of a collision tumor: a B1B2 thymoma and a small lymphocytic lymphoma. Flow cytometry of the peripheral blood revealed the presence of a small number of leukemic cells. After postoperative irradiation of the mediastinum and chemotherapy a complete response in both diseases was achieved. The case confirms that a pathologist should always be aware that two different neoplasms can coexist in rare cases.
我们报告一例52岁患有重症肌无力和纵隔肿瘤的男性患者,他因手术治疗入院。切除肿瘤的病理检查显示为一种非常罕见的碰撞瘤:B1B2型胸腺瘤和小淋巴细胞淋巴瘤。外周血流式细胞术显示存在少量白血病细胞。纵隔术后放疗和化疗后,两种疾病均实现完全缓解。该病例证实病理学家应始终意识到在罕见情况下两种不同的肿瘤可能共存。