Gómez Saúl, León Tomás, Macuer Maximiliano, Alves Mariana, Ruiz Sergio
Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Departamento de Psiquiatría, Centro Interdisciplinario de Neurociencias, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Med Chil. 2017 Mar;145(3):351-359. doi: 10.4067/S0034-98872017000300009.
Growing information has emphasized the risk of benzodiazepines (BZD), particularly among the elderly. However, the information available in Latin America is scarce.
to review the available information on the use of BZD in older adults in Latin America to achieve an overview of the information currently available, and a thorough understanding of this phenomenon in our region.
A systematic review with MeSH terms elderly, latinamerican and benzodiazepines was performed in PubMed and with each Latin American country. A search in databases SciELO and LILACS was also performed. In all, 126 items of finally selected 21 that met the inclusion criteria.
Studies show that consumption of benzodiazepines in the elderly population in Latin America is high, with a preponderance of long half-life benzodiazepines in women, and frequent self-medication.
The revised articles establish the importance of further study of the phenomenon of the use of benzodiazepines in our elderly population. Strikingly, scientific information is scarce, with most studies coming from only one country (Brazil). Moreover, most of them are transversal and descriptive, with few studies that explore long-term side effects, or specific hypotheses. Further studies should address these important issues.
越来越多的信息强调了苯二氮䓬类药物（BZD）的风险，尤其是在老年人中。然而，拉丁美洲现有的相关信息却很匮乏。
回顾拉丁美洲老年人使用BZD的现有信息，以全面了解目前可得的信息，并深入认识该地区的这一现象。
在PubMed以及每个拉丁美洲国家，使用医学主题词“老年人”“拉丁美洲”和“苯二氮䓬类药物”进行系统综述。还在数据库SciELO和LILACS中进行了检索。最终从126篇文献中筛选出21篇符合纳入标准的文献。
研究表明，拉丁美洲老年人群中苯二氮䓬类药物的消费量很高，女性中长半衰期苯二氮䓬类药物占优势，且存在大量自我用药的情况。
经修订的文章证实了进一步研究我国老年人群使用苯二氮䓬类药物这一现象的重要性。令人惊讶的是，科学信息匮乏，大多数研究仅来自一个国家（巴西）。此外，大多数研究都是横向和描述性的，很少有研究探讨长期副作用或特定假设。未来的研究应解决这些重要问题。
