Majumder Partha P, Nayak Sujata, Bhattacharya S K, Ghosh K K, Pal S, Mukherjee B N
Indian Statistical Institute, Calcutta, India.
S.S.K.M. Hospital, Calcutta, India.
Am J Hum Biol. 1994;6(2):183-194. doi: 10.1002/ajhb.1310060206.
This population based study was conducted among the Marwaris of Calcutta, India. A total of 1,096 individuals from 151 randomly selected families were studied. Mean blood pressures were high. About 17% of the population was hypertensive, i.e., systolic blood pressure > 160 mm Hg and/or diastolic blood pressure > 95 mm Hg. The mean value of the ratio of total cholesterol to HDL cholesterol was 4.75. Comparison with a rural agricultural population showed that unadjusted blood pressure profiles differed significantly, but not when the profiles were adjusted for variation in concomitants (e.g., age, weight, fatness, etc.). It is hypothesized that the "intrinsic" blood pressure profiles of both populations are similar and that genes influencing physical variables (e.g., fatness) do not directly influence blood pressure. © 1994 Wiley-Liss, Inc.
这项基于人群的研究是在印度加尔各答的马尔瓦尔人当中开展的。对随机选取的151个家庭中的1096名个体进行了研究。平均血压较高。约17%的人群患有高血压,即收缩压>160毫米汞柱和/或舒张压>95毫米汞柱。总胆固醇与高密度脂蛋白胆固醇的比值平均值为4.75。与农村农业人口的比较表明,未经调整的血压情况有显著差异,但在对伴随因素(如年龄、体重、肥胖等)的变化进行调整后则无差异。据推测,这两个人群的“内在”血压情况相似,且影响身体变量(如肥胖)的基因不会直接影响血压。© 1994威利 - 利斯公司。