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Long-term Follow-up of Patients With Retinitis Pigmentosa Receiving Intraocular Ciliary Neurotrophic Factor Implants.接受眼内睫状神经营养因子植入的色素性视网膜炎患者的长期随访
Am J Ophthalmol. 2016 Oct;170:10-14. doi: 10.1016/j.ajo.2016.07.013. Epub 2016 Jul 25.
2
Sustained Delivery of Bioactive GDNF from Collagen and Alginate-Based Cell-Encapsulating Gel Promoted Photoreceptor Survival in an Inherited Retinal Degeneration Model.基于胶原蛋白和藻酸盐的细胞封装凝胶对生物活性胶质细胞源性神经营养因子的持续递送促进了遗传性视网膜变性模型中光感受器的存活。
PLoS One. 2016 Jul 21;11(7):e0159342. doi: 10.1371/journal.pone.0159342. eCollection 2016.
3
Ciliary neurotrophic factor for macular telangiectasia type 2: results from a phase 1 safety trial.用于2型黄斑毛细血管扩张症的睫状神经营养因子：1期安全性试验结果
Am J Ophthalmol. 2015 Apr;159(4):659-666.e1. doi: 10.1016/j.ajo.2014.12.013. Epub 2014 Dec 19.
4
Drug delivery techniques for treating age-related macular degeneration.治疗年龄相关性黄斑变性的药物输送技术。
Expert Opin Drug Deliv. 2014 Jan;11(1):61-8. doi: 10.1517/17425247.2013.859135. Epub 2013 Nov 13.
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Randomized trial of ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for retinitis pigmentosa.包裹细胞眼内植入物递送睫状神经营养因子治疗色素性视网膜炎的随机试验。
Am J Ophthalmol. 2013 Aug;156(2):283-292.e1. doi: 10.1016/j.ajo.2013.03.021. Epub 2013 May 10.
6
Two-year intraocular delivery of ciliary neurotrophic factor by encapsulated cell technology implants in patients with chronic retinal degenerative diseases.采用细胞包封技术的植入物进行睫状神经营养因子的两年眼内递释，用于治疗慢性视网膜退行性疾病。
Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7484-91. doi: 10.1167/iovs.12-9970.
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Optimization of 100 μm alginate-poly-L-lysine-alginate capsules for intravitreous administration.优化 100μm 海藻酸钠-聚-L-赖氨酸-海藻酸钠微胶囊用于玻璃体内给药。
J Control Release. 2012 Mar 28;158(3):443-50. doi: 10.1016/j.jconrel.2011.09.079. Epub 2011 Sep 24.
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Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration.包裹细胞眼内植入物递送睫状神经营养因子治疗年龄相关性黄斑变性的地图样萎缩。
Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6241-5. doi: 10.1073/pnas.1018987108. Epub 2011 Mar 28.
9
Drug carrier systems based on collagen-alginate composite structures for improving the performance of GDNF-secreting HEK293 cells.基于胶原蛋白-海藻酸盐复合结构的药物载体系统，用于改善分泌胶质细胞源性神经营养因子的人胚肾293细胞的性能。
Biomaterials. 2009 Feb;30(6):1214-21. doi: 10.1016/j.biomaterials.2008.11.017. Epub 2008 Dec 6.
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Alginate-based microencapsulation of retinal pigment epithelial cell line for cell therapy.用于细胞治疗的基于藻酸盐的视网膜色素上皮细胞系微囊化
Biomaterials. 2008 Mar;29(7):869-76. doi: 10.1016/j.biomaterials.2007.10.056. Epub 2007 Nov 28.

Delivery of therapeutics to posterior eye segment: cell-encapsulating systems.

作者信息

Wong Francisca S Y, Tsang Ken K, Lo Amy C Y

机构信息

Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.

Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.

出版信息

Neural Regen Res. 2017 Apr;12(4):576-577. doi: 10.4103/1673-5374.205093.

DOI:10.4103/1673-5374.205093
PMID:28553333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5436351/
Abstract
摘要