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白藜芦醇对淋巴瘤和白血病细胞的细胞及分子靶点

Cellular and Molecular Targets of Resveratrol on Lymphoma and Leukemia Cells.

作者信息

Frazzi Raffaele, Guardi Manuela

机构信息

Laboratory of Translational Research, Arcispedale S. Maria Nuova IRCCS, Viale Risorgimento 80, 42124 Reggio Emilia, Italy.

出版信息

Molecules. 2017 May 27;22(6):885. doi: 10.3390/molecules22060885.

DOI:10.3390/molecules22060885
PMID:28555002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6152792/
Abstract

Resveratrol (RSV) is a well known chemopreventive molecule featuring anti-cancer properties. Our paper describes the main molecular targets of RSV linked to its antiproliferative activity on lymphoma and leukemia experimental models. It discusses further the most recent and most promising among these molecular targets for a translational application.

摘要

白藜芦醇（RSV）是一种具有抗癌特性的著名化学预防分子。我们的论文描述了RSV与淋巴瘤和白血病实验模型的抗增殖活性相关的主要分子靶点。它进一步讨论了这些分子靶点中最具创新性和前景的用于转化应用的靶点。

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Sci Rep. 2016 Nov 21;6:37417. doi: 10.1038/srep37417.
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Resveratrol induces cell cycle arrest and apoptosis in human eosinophils from asthmatic individuals.白藜芦醇可诱导哮喘患者的人嗜酸性粒细胞发生细胞周期阻滞和凋亡。
Mol Med Rep. 2016 Dec;14(6):5231-5236. doi: 10.3892/mmr.2016.5884. Epub 2016 Oct 25.
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Multiplicity of effects and health benefits of resveratrol.白藜芦醇的多重效应与健康益处
Curr Med Chem. 2024 May 3. doi: 10.2174/0109298673290941240430171146.
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S1PR1/S1PR3-YAP signaling and S1P-ALOX15 signaling contribute to an aggressive behavior in obesity-lymphoma.S1PR1/S1PR3-YAP 信号和 S1P-ALOX15 信号有助于肥胖症-淋巴瘤中的侵袭性行为。
J Exp Clin Cancer Res. 2023 Jan 5;42(1):3. doi: 10.1186/s13046-022-02589-7.
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Chronic myeloid leukemia stem cells: targeting therapeutic implications.慢性髓性白血病干细胞：靶向治疗的意义。
Stem Cell Res Ther. 2021 Dec 18;12(1):603. doi: 10.1186/s13287-021-02659-1.
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Resveratrol, EGCG and Vitamins Modulate Activated T Lymphocytes.白藜芦醇、EGCG 和维生素调节活化的 T 淋巴细胞。
Molecules. 2021 Sep 15;26(18):5600. doi: 10.3390/molecules26185600.
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Medicina (Kaunas). 2016;52(3):148-55. doi: 10.1016/j.medici.2016.03.003. Epub 2016 Apr 7.
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