Chartrain Alexander G, Kurt Mehmet, Yao Amy, Feng Rui, Nael Kambiz, Mocco J, Bederson Joshua B, Balchandani Priti, Shrivastava Raj K
Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, Annenberg 8, One Gustave L Levy Pl, New York, NY, 10029, USA.
Department of Mechanical Engineering, Stevens Institute of Technology, Hoboken, NJ, 07030, USA.
Neurosurg Rev. 2019 Mar;42(1):1-7. doi: 10.1007/s10143-017-0862-8. Epub 2017 May 31.
Meningioma consistency is a critical factor that influences preoperative planning for surgical resection. Recent studies have investigated the utility of preoperative magnetic resonance elastography (MRE) in predicting meningioma consistency. However, it is unclear whether existing methods are optimal for application to clinical practice. The results and conclusions of these studies are limited by their imaging acquisition methods, such as the use of a single MRE frequency and the use of shear modulus as the final measurement variable, rather than its storage and loss modulus components. In addition, existing studies do not account for the effects of cranial anatomy, which have been shown to significantly distort the MRE signal. Given the interaction of meningiomas with these anatomic structures and the lack of supporting evidence with more accurate imaging parameters, MRE may not yet be reliable for use in clinical practice.
脑膜瘤的质地是影响手术切除术前规划的关键因素。近期研究探讨了术前磁共振弹性成像（MRE）在预测脑膜瘤质地方面的效用。然而，尚不清楚现有方法是否最适合应用于临床实践。这些研究的结果和结论受到其成像采集方法的限制，例如使用单一的MRE频率以及将剪切模量作为最终测量变量，而非其储存模量和损耗模量分量。此外，现有研究未考虑颅骨解剖结构的影响，而颅骨解剖结构已被证明会显著扭曲MRE信号。鉴于脑膜瘤与这些解剖结构的相互作用以及缺乏更准确成像参数的支持证据，MRE在临床实践中的应用可能尚不具有可靠性。
