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[头皮银屑病和脂溢性皮炎]

[Psoriasis capitis and seborrhoic eczema of scalp diseases].

作者信息

Sticherling M

机构信息

Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.

出版信息

Hautarzt. 2017 Jun;68(6):457-465. doi: 10.1007/s00105-017-3986-4.

DOI:10.1007/s00105-017-3986-4
PMID:28567508
Abstract

The scalp may be affected by various diseases with equally varying manifestations. Erythema and scaling is often accompanied by agonizing itch. Scalp psoriasis and seborrheic eczema represent the most frequent diseases, which can be differentiated into classical cases; however, overlap and similarities are seen. Sharply demarcated erythematosquamous plaques across the natural hairline in psoriasis are opposed to blurred dark-red erythema and yellowish, greasy scales in seborrheic eczema. Whereas with the latter diffuse alopecia may frequently be found, hair loss is rarely seen in psoriasis and may also be related to therapeutic agents. Treatment is based on acuity as well as extent of disease and individual life quality aspects of the patients. It is mainly based on topical corticosteroids, combined with vitamin D derivatives in psoriasis and antimycotic agents in seborrheic eczema. In severe cases and widespread psoriatic disease, systemic treatment may be necessary, including the classic agents methotrexate, fumarates and ciclosporin as well as biologicals. Systemic treatment of seborrheic eczema is rarely necessary and resides on corticosteroids, antimycotic agents and vitamin A derivatives. In addition, intensive counseling of patients on the necessity of consequent and long-term treatment as well as use of mild skin care products is mandatory.

摘要

头皮可能会受到各种疾病的影响,其表现也各不相同。红斑和脱屑常常伴有剧烈瘙痒。头皮银屑病和脂溢性皮炎是最常见的疾病,可分为典型病例;然而,也存在重叠和相似之处。银屑病中跨越自然发际线的边界清晰的红斑鳞屑斑块与脂溢性皮炎中边界模糊的暗红色红斑及淡黄色油腻鳞屑形成对比。后者常伴有弥漫性脱发,而银屑病中很少见脱发,且脱发也可能与治疗药物有关。治疗基于疾病的严重程度、范围以及患者的个人生活质量等方面。主要基于局部使用皮质类固醇,银屑病中联合使用维生素D衍生物,脂溢性皮炎中使用抗真菌药物。在严重和广泛的银屑病病例中,可能需要进行全身治疗,包括经典药物甲氨蝶呤、富马酸盐和环孢素以及生物制剂。脂溢性皮炎很少需要全身治疗,主要使用皮质类固醇、抗真菌药物和维生素A衍生物。此外,必须对患者进行强化咨询,告知其坚持长期治疗的必要性以及使用温和护肤品的重要性。

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[Allergic contact dermatitis of the scalp].[头皮过敏性接触性皮炎]
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Collapse of human scalp microbiome network in dandruff and seborrhoeic dermatitis.头皮屑和脂溢性皮炎中人类头皮微生物组网络的崩溃。
Exp Dermatol. 2017 Sep;26(9):835-838. doi: 10.1111/exd.13293. Epub 2017 Apr 11.
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Low-dose oral isotretinoin for moderate to severe seborrhea and seborrheic dermatitis: a randomized comparative trial.低剂量口服异维A酸治疗中度至重度脂溢性皮炎:一项随机对照试验。
Int J Dermatol. 2017 Jan;56(1):80-85. doi: 10.1111/ijd.13408. Epub 2016 Oct 25.
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Managing Scalp Psoriasis: An Evidence-Based Review.头皮银屑病的管理:基于证据的综述。
Am J Clin Dermatol. 2017 Feb;18(1):17-43. doi: 10.1007/s40257-016-0222-4.
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Histopathological Differential Diagnosis of Psoriasis and Seborrheic Dermatitis of the Scalp.头皮银屑病与脂溢性皮炎的组织病理学鉴别诊断
Ann Dermatol. 2016 Aug;28(4):427-32. doi: 10.5021/ad.2016.28.4.427. Epub 2016 Jul 26.
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Scalp psoriasis and biologic agents: a retrospective, comparative study from a tertiary psoriasis referral centre.头皮银屑病与生物制剂:一项来自三级银屑病转诊中心的回顾性比较研究
J Eur Acad Dermatol Venereol. 2016 Dec;30(12):2091-2096. doi: 10.1111/jdv.13780. Epub 2016 Jul 13.
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Topical treatments for scalp psoriasis.头皮银屑病的局部治疗
Cochrane Database Syst Rev. 2016 Feb 26;2(2):CD009687. doi: 10.1002/14651858.CD009687.pub2.
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Malassezia species in healthy skin and in dermatological conditions.健康皮肤和皮肤病中的马拉色菌属。
Int J Dermatol. 2016 May;55(5):494-504. doi: 10.1111/ijd.13116. Epub 2015 Dec 29.
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Current management of scalp psoriasis.头皮银屑病的当前管理
Skin Therapy Lett. 2015 May-Jun;20(3):5-7.
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Psoriatic alopecia.银屑病性脱发
Clin Exp Dermatol. 2015 Oct;40(7):717-21. doi: 10.1111/ced.12715. Epub 2015 Jul 23.