Sticherling M
Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
Hautarzt. 2017 Jun;68(6):457-465. doi: 10.1007/s00105-017-3986-4.
The scalp may be affected by various diseases with equally varying manifestations. Erythema and scaling is often accompanied by agonizing itch. Scalp psoriasis and seborrheic eczema represent the most frequent diseases, which can be differentiated into classical cases; however, overlap and similarities are seen. Sharply demarcated erythematosquamous plaques across the natural hairline in psoriasis are opposed to blurred dark-red erythema and yellowish, greasy scales in seborrheic eczema. Whereas with the latter diffuse alopecia may frequently be found, hair loss is rarely seen in psoriasis and may also be related to therapeutic agents. Treatment is based on acuity as well as extent of disease and individual life quality aspects of the patients. It is mainly based on topical corticosteroids, combined with vitamin D derivatives in psoriasis and antimycotic agents in seborrheic eczema. In severe cases and widespread psoriatic disease, systemic treatment may be necessary, including the classic agents methotrexate, fumarates and ciclosporin as well as biologicals. Systemic treatment of seborrheic eczema is rarely necessary and resides on corticosteroids, antimycotic agents and vitamin A derivatives. In addition, intensive counseling of patients on the necessity of consequent and long-term treatment as well as use of mild skin care products is mandatory.
头皮可能会受到各种疾病的影响,其表现也各不相同。红斑和脱屑常常伴有剧烈瘙痒。头皮银屑病和脂溢性皮炎是最常见的疾病,可分为典型病例;然而,也存在重叠和相似之处。银屑病中跨越自然发际线的边界清晰的红斑鳞屑斑块与脂溢性皮炎中边界模糊的暗红色红斑及淡黄色油腻鳞屑形成对比。后者常伴有弥漫性脱发,而银屑病中很少见脱发,且脱发也可能与治疗药物有关。治疗基于疾病的严重程度、范围以及患者的个人生活质量等方面。主要基于局部使用皮质类固醇,银屑病中联合使用维生素D衍生物,脂溢性皮炎中使用抗真菌药物。在严重和广泛的银屑病病例中,可能需要进行全身治疗,包括经典药物甲氨蝶呤、富马酸盐和环孢素以及生物制剂。脂溢性皮炎很少需要全身治疗,主要使用皮质类固醇、抗真菌药物和维生素A衍生物。此外,必须对患者进行强化咨询,告知其坚持长期治疗的必要性以及使用温和护肤品的重要性。