Okuyama Teruhiro
RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), 46-5261, 43 Vassar Street, Cambridge, MA 02139, USA.
Neurosci Res. 2018 Apr;129:17-23. doi: 10.1016/j.neures.2017.05.007. Epub 2017 Jun 1.
Social memory is one of the crucial components of episodic memories. Gregarious animals living in societies utilize social memory to exhibit the appropriate social behaviors such as aggression, avoidance, cooperative behavior, and even mating behavior. However, the neural mechanisms underlying social memory in the hippocampus remains mysterious. Here, I review some evidence from work done in rodents and primates on the brain region(s) and circuits encoding and/or retrieving social memory, as well as a storage for social memory (i.e. social memory engram neurons). Based on our recent findings that neural ensemble in ventral CA1 sub-region of the hippocampus possesses social memory engram, I would discuss the neural network for social information processing in order to encode social memory; and its evolutionary conservation between rodents and human.
社会记忆是情景记忆的关键组成部分之一。生活在群体中的群居动物利用社会记忆来展现适当的社会行为，如攻击、回避、合作行为，甚至交配行为。然而，海马体中社会记忆背后的神经机制仍然神秘。在这里，我回顾了一些来自啮齿动物和灵长类动物研究的证据，这些研究涉及编码和/或检索社会记忆的脑区和神经回路，以及社会记忆的存储（即社会记忆印迹神经元）。基于我们最近的发现，即海马体腹侧CA1子区域的神经集群拥有社会记忆印迹，我将讨论用于编码社会记忆的社会信息处理神经网络；以及它在啮齿动物和人类之间的进化保守性。
